ArticleJOR spine2020
Influence of testing environment and loading rate on intervertebral disc compressive mechanics: An assessment of repeatability at three different laboratories.
Article in JOR spine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 29 citations in OpenAlex.
- Biomechanical Advantages of Novel Duet Screws Plus Bilateral Satellite Rods Fixation in the Correction Surgery for Adult Spinal Deformity.Orthopaedic surgery · 2025Trial
- Chondroitinase Versus Papain Digestion Leads to Different Outcome for In Vitro Simulation of Degenerated Discs.JOR spine · 2026Article
- Evaluation of internal fixation stability of distal humerus C-type fractures based on musculoskeletal dynamics: finite element analysis under dynamic loading.Journal of orthopaedic surgery and research · 2025Article
- SiACS biomaterials science & engineering · 2025Article
- The next frontier in healthcare: perspectives and discussion on building trust and societal acceptance of digital humans in the essential framework of impact biomechanics.Frontiers in bioengineering and biotechnology · 2025Review
- Higher interfragmentary compression force improves lateral tibial plateau fracture stability using locking plate fixation: experimental and simulation verification.BMC musculoskeletal disorders · 2024Article
- Application of a combined cancellous lag screw enhances the stability of locking plate fixation of osteoporotic lateral tibial plateau fracture by providing interfragmentary compression force.Journal of orthopaedic surgery and research · 2024Article
- CT-based finite element simulating spatial bone damage accumulation predicts metastatic human vertebrae strength and stiffness.Frontiers in bioengineering and biotechnology · 2024Article
- Effectivity of puncture method for intervertebral disc degeneration animal models: review article.Annals of medicine and surgery (2012) · 2023Article
- Quantifying internal intervertebral disc strains to assess nucleus replacement device designs: a digital volume correlation and ultra-high-resolution MRI study.Frontiers in bioengineering and biotechnology · 2023Article
- Disc geometry measurement methods affect reported compressive mechanics by up to 65.JOR spine · 2022Article
- In Vitro Studies for Investigating Creep of Intervertebral Discs under Axial Compression: A Review of Testing Environment and Results.Materials (Basel, Switzerland) · 2022Review
- Spine biomechanical testing methodologies: The controversy of consensus vs scientific evidence.JOR spine · 2021Review
- A Robust Multiscale and Multiphasic Structure-Based Modeling Framework for the Intervertebral Disc.Frontiers in bioengineering and biotechnology · 2021Article
- Improving reproducibility in spine research.JOR spine · 2020Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In vitro mechanical testing of intervertebral discs is crucial for basic science and pre-clinical testing. Generally, these tests aim to replicate in vivo conditions, but simplifications are necessary in specimen preparation and mechanical testing due to complexities in both structure and the loading conditions required to replicate in vivo conditions. There has been a growing interest in developing a consensus of testing protocols within the spine community to improve comparison of results between studies. The objective of this study was to perform axial compression experiments on bovine bone-disc-bone specimens at three institutions. No differences were observed between testing environment being air, with PBS soaked gauze, or a PBS bath (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.