Evidence map›Paper›PMID 33015533›Full record

ArticleJCO precision oncology2020

Erik A Williams, Radwa Sharaf, Brennan Decker, Adrienne J Werth, Helen Toma, Meagan Montesion, Ethan S Sokol, Dean C Pavlick, Nikunj Shah, Kevin Jon Williams and 7 more

Open access · bronzeAbstract read
In one paragraph

Article in JCO precision oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Integrative Analysis of the Role ofCurrent issues in molecular biology · 2023
    Article
  3. Molecular-Based Immunohistochemical Algorithm for Uterine Leiomyosarcoma Diagnosis.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2023
    Article
  4. Article
  5. High-LevelOphthalmology science · 2022
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 1 country.

Erik A WilliamsFoundation Medicine, Cambridge, MA.
Radwa SharafFoundation Medicine, Cambridge, MA.
Brennan DeckerDepartment of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
Adrienne J WerthChristiana Hospital, Department of Obstetrics and Gynecology, Newark, DE.
Helen TomaChristiana Hospital, Department of Obstetrics and Gynecology, Newark, DE.
Meagan MontesionFoundation Medicine, Cambridge, MA.
Ethan S SokolFoundation Medicine, Cambridge, MA.
Dean C PavlickFoundation Medicine, Cambridge, MA.
Nikunj ShahFoundation Medicine, Cambridge, MA.
Kevin Jon WilliamsDepartment of Physiology, Department of Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, PA.
Jeffrey M VenstromFoundation Medicine, Cambridge, MA.
Brian M AlexanderFoundation Medicine, Cambridge, MA.
Jeffrey S RossFoundation Medicine, Cambridge, MA.
Lee A AlbackerFoundation Medicine, Cambridge, MA.
Douglas I LinFoundation Medicine, Cambridge, MA.
Shakti H RamkissoonFoundation Medicine, Cambridge, MA.
Julia A ElvinFoundation Medicine, Cambridge, MA.
Foundation Medicine (United States)Harvard University · USBrigham and Women's Hospital · USChristiana Hospital · USSUNY Upstate Medical University · USTemple University · USWake Forest University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLeiomyosarcoma (LMS) harbors frequent mutations in

methodsTissues from 276,645 unique advanced cancers, including 2,570 uterine and soft tissue LMS, were sequenced by hybrid-capture-based next-generation DNA and RNA sequencing/comprehensive genomic profiling of up to 406 genes. We characterized clinicopathologic features of relevant patient cases.

resultsOverall, 77 LMS exhibited homozygous copy loss of

conclusion

Identifiers

PMID33015533
PMCPMC7529542
OpenAlexW3082189156

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.