Evidence map›Paper›PMID 33015315›Full record

ArticleInternational journal of cardiology. Heart & vasculature2020

The Cone Flare Crush Modified-T (CFCT) stenting technique for coronary artery bifurcation lesions.

William T Peverill, Alexander Incani, Stephen G Worthley, Yash Singbal, Paul J Garrahy, Andrew B McCann, Stephen V Cox, Peter T Moore, Richard Y Y Lim, Taufik Fetahovic and 4 more

Open access · goldAbstract read
In one paragraph

Article in International journal of cardiology. Heart & vasculature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

William T PeverillDepartment of Cardiology, Princess Alexandra Hospital, Brisbane, QLD 4102, Australia.
Alexander IncaniUniversity of Queensland, Brisbane, QLD 4102, Australia.
Stephen G WorthleyGenesisCare, Building 11 The Mill, Alexandria, Sydney, NSW 2015 Australia.
Yash SingbalDepartment of Cardiology, Princess Alexandra Hospital, Brisbane, QLD 4102, Australia.
Paul J GarrahyDepartment of Cardiology, Princess Alexandra Hospital, Brisbane, QLD 4102, Australia.
Andrew B McCannDepartment of Cardiology, Princess Alexandra Hospital, Brisbane, QLD 4102, Australia.
Stephen V CoxDepartment of Cardiology, Princess Alexandra Hospital, Brisbane, QLD 4102, Australia.
Peter T MooreDepartment of Cardiology, Princess Alexandra Hospital, Brisbane, QLD 4102, Australia.
Richard Y Y LimDepartment of Cardiology, Princess Alexandra Hospital, Brisbane, QLD 4102, Australia.
Taufik FetahovicDepartment of Cardiology, Princess Alexandra Hospital, Brisbane, QLD 4102, Australia.
Gerard W ConnorsDepartment of Cardiology, Princess Alexandra Hospital, Brisbane, QLD 4102, Australia.
Cindy HallDepartment of Cardiology, Princess Alexandra Hospital, Brisbane, QLD 4102, Australia.
Charmaine SiegDepartment of Cardiology, Princess Alexandra Hospital, Brisbane, QLD 4102, Australia.
Anthony C CamugliaDepartment of Cardiology, Princess Alexandra Hospital, Brisbane, QLD 4102, Australia.
The University of Queensland · AUSt Andrew’s Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe present study is a prospective observational single arm clinical investigation, with parallel bench test interrogation, aimed at investigating the technical feasibility, safety and clinical outcomes with the cone flare crush modified-T (CFCT) bifurcation stenting technique. Bifurcation percutaneous coronary intervention (PCI) remains an area of ongoing procedural evolution. More widely applicable and reproducible techniques are required.

methodsFrom April 2018 until March 2019, 20 consecutive patients underwent bifurcation PCI using the CFCT technique with a Pt-Cr everolimus drug-eluting stent with a bioresorbable polymer. Exercise stress echocardiography was performed at 12-month follow-up. The primary outcome was a composite of cardiac related mortality, myocardial infarction, target lesion/vessel revascularization and stroke. Safety secondary endpoints included bleeding, all-cause mortality and stent thrombosis.

resultsAll patients underwent a successful CFCT bifurcation procedure with no complications to 30-day follow-up. One patient met the primary endpoint requiring target lesion revascularization at 9 months for stable angina. There were no other primary or secondary outcome events in the cohort. There were no strokes, deaths, stent thrombosis or myocardial infarction during the follow-up period. The mean CCS score improved from 2.25 to 0.25 (p < 0.0001). Optical coherence tomography (OCT) and bench test findings indicated optimal side branch ostial coverage and minimal redundant strut material crowding the neo-carina.

conclusionsThe CFCT technique appears to be a safe, efficacious and feasible strategy for managing coronary artery bifurcation disease. Expanded and randomized datasets with longer term follow-up are required to further explore confirm this feasibility data. (ANZCTR ID: ACTRN12618001145291).

Indexed as

ACS, Acute coronary syndromeACT, Activated clotting timeAHA, American Heart AssociationARC, Academic Research ConsortiumBARC, British Academic Research ConsortiumCABG, Coronary artery bypass graftingCCS, Canadian Cardiovascular SocietyCFCT, Cone Flare Crush Modified-TCFI, Cone Flare InflationDAPT, Dual antiplatelet therapyDES, Drug Eluting StentDMV, Distal main vesselDrug Eluting Stent (DES)DSE, Dobutamine stress echocardiographyESE, Exercise stress echocardiographyISKB, Intermediary simultaneous kissing balloonISR, In stent restenosisLAD, Left anterior descending arteryLCx, Left circumflex arteryLMCA, Left main coronary arteryMACCE, Major adverse cardiac and cerebrovascular eventMI, Myocardial infarctMRA, Mechanical rotational atherectomyMV, Main VesselNSTEMI, Non-ST elevation Myocardial InfarctionNYHA, New York heart associationOCT, Optical coherence tomographyPCI, Percutaneous Coronary InterventionPercutaneous Coronary Intervention (PCI)PMV, Proximal main vesselPOT, Proximal Optimisation TechniquePUKBI, Penultimate kissing balloon inflationQCA, Quantitative Coronary AngiographyRBP, Rated Burst PressureSB, Side BranchSEM, Standard Error of the meanSTEMI, ST elevation Myocardial InfarctionStenting technique (STEC)ST, Stent thrombosisSYNTAX, Synergy Between Percutaneous Coronary Intervention with Taxus and Cardiac SurgeryTLR, Target Lesion RevascularisationTVR, Target Vessel RevascularisationUAP, Unstable angina pectoris

Identifiers

PMID33015315
PMCPMC7522340
OpenAlexW3088768661

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.