Evidence map›Paper›PMID 33015169›Full record

ReviewBioMed research international2020

Antibody-Based Immunotherapeutic Strategies for the Treatment of Hematological Malignancies.

Yizhao Han, Zhuojun Liu, Jia Liu, Weiqi Yan, Yuanshi Xia, Shuhua Yue, Jian Yu

Open access · hybridAbstract readReview
In one paragraph

Review in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. The role of DNA mismatch repair in immunotherapy of human cancer.International journal of biological sciences · 2022
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yizhao HanBeijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing 100083, China.
Zhuojun LiuBeijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing 100083, China.
Jia LiuBeijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing 100083, China.
Weiqi YanBeijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing 100083, China.
Yuanshi XiaSchool of Biological Science and Medical Engineering, Beihang University, Beijing 100083, China.
Shuhua YueSchool of Biological Science and Medical Engineering, Beihang University, Beijing 100083, China.ORCID https://orcid.org/0000-0003-1830-008X
Jian YuBeijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing 100083, China.ORCID https://orcid.org/0000-0002-2774-6270
Beijing Advanced Sciences and Innovation Center · CNBeihang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the most common type of cancer in the world, hematological malignancies (HM) account for 10% of all annual cancer deaths and have attracted more attention. Conventional treatments, such as chemotherapy, radiotherapy, and hematopoietic stem cell transplantation (HSCT), could relieve patients suffering HM. However, serious side effects and high costs bring patients both physical complaints and mental pressure. Recently, compared with conventional therapeutic strategies for HM patients, antibody-based immunotherapies, including cancer vaccines, oncolytic virus therapies, monoclonal antibody treatments, and CAR-T cell therapies, have displayed longer survival time and fewer adverse reactions, even though specific efficacy and safety of these antibody-based immunotherapies still need to be evaluated and improved. This review summarized the advantages of antibody-based immunotherapies over conventional treatments, as well as its existing difficulties and solutions, thereby enhancing the understanding and applications of antibody-based immunotherapies in HM treatment.

Indexed as

AnimalsAntibodiesCancer VaccinesHematologic NeoplasmsHumansImmunotherapyAntibodiesCancer Vaccines

Identifiers

PMID33015169
PMCPMC7519992
OpenAlexW3087740641

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.