Evidence map›Paper›PMID 33015128›Full record

ReviewFrontiers in nutrition2020

Epigenetic Regulation and Dietary Control of Triple Negative Breast Cancer.

Ornella I Selmin, Micah G Donovan, Barbara J Stillwater, Leigh Neumayer, Donato F Romagnolo

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. CRISPR/Cas9-mediatedHorticulture research · 2025
    Article
  6. Methylation ofMedComm · 2023
    Article
  7. The Aryl Hydrocarbon Receptor, Epigenetics and the Aging Process.The journal of nutrition, health & aging · 2023
    Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ornella I SelminDepartment of Nutritional Sciences, The University of Arizona, Tucson, AZ, United States.
Micah G DonovanUniversity of Arizona Cancer Center, The University of Arizona, Tucson, AZ, United States.
Barbara J StillwaterDepartment of Surgery, Breast Surgery Oncology, The University of Arizona, Tucson, AZ, United States.
Leigh NeumayerDepartment of Surgery, Breast Surgery Oncology, The University of Arizona, Tucson, AZ, United States.
Donato F RomagnoloDepartment of Nutritional Sciences, The University of Arizona, Tucson, AZ, United States.
University of Arizona · USUniversity of Arizona Cancer Center

Funding

VITAMIN AP30CA023074 · NCI · UNIVERSITY OF ARIZONA · PI Dan Theodorescu · 1985 to 2026
$110.2M
Integrative Cancer Scholars Training GrantT32CA009213 · NCI · UNIVERSITY OF ARIZONA · PI CAREW, JENNIFER S, CURIEL-LEWANDROWSKI, CLARA · 1985 to 2024
$8.6M
NCI NIH HHS P30 CA023074NCI NIH HHS T32 CA009213
6 · The paper itself

Abstract

Triple negative breast cancer (TNBC) represents a highly heterogeneous group of breast cancers, lacking expression of the estrogen (ER) and progesterone (PR) receptors, and human epidermal growth factor receptor 2 (HER2). TNBC are characterized by a high level of mutation and metastasis, poor clinical outcomes and overall survival. Here, we review the epigenetic mechanisms of regulation involved in cell pathways disrupted in TNBC, with particular emphasis on dietary food components that may be exploited for the development of effective strategies for management of TNBC.

Indexed as

dietary bioactive compoundsDNA methylationepigenetic regulationtriple negative breast cancertumor suppressor

Identifiers

PMID33015128
PMCPMC7506147
OpenAlexW3082485175

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.