Evidence map›Paper›PMID 33015095›Full record

ArticleFrontiers in medicine2020

Expression of a Human Caveolin-1 Mutation in Mice Drives Inflammatory and Metabolic Defect-Associated Pulmonary Arterial Hypertension.

Anandharajan Rathinasabapathy, Courtney Copeland, Amber Crabtree, Erica J Carrier, Christy Moore, Sheila Shay, Santhi Gladson, Eric D Austin, Anne K Kenworthy, James E Loyd and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Anandharajan RathinasabapathyAllergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.
Courtney CopelandPulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Amber CrabtreeAllergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.
Erica J CarrierAllergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.
Christy MooreAllergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.
Sheila ShayAllergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.
Santhi GladsonAllergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.
Eric D AustinPediatrics, Vanderbilt University Medical Center, Nashville, TN, United States.
Anne K KenworthyMolecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN, United States.
James E LoydAllergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.
Anna R HemnesAllergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.
James D WestAllergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.
Vanderbilt University Medical Center · USHarvard University · USVanderbilt University · US

Funding

Mechanisms of Familial Pulmonary FibrosisP01HL092870 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BLACKWELL, TIMOTHY S. · 2010 to 2020
$21.6M
Vanderbilt Mouse Metabolic Physiology CenterU24DK059637 · NIDDK · VANDERBILT UNIVERSITY · PI WASSERMAN, DAVID H · 2001 to 2015
$14.9M
Interventions Against the Molecular Etiology of BMPR2-induced PAHR01HL095797 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WEST, JAMES D · 2010 to 2022
$6.7M
Caveolar Defects Underlie the Genetic Origins of PAHR01HL111259 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KENWORTHY, ANNE K, LOYD, JAMES E · 2012 to 2016
$3.5M
Role of the thromboxane prostanoid receptor in right ventricular adaptation to pressure overloadR01HL135011 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CARRIER, ERICA J · 2017 to 2021
$2.2M
Comprehensive Laboratory Animal Measurement System (CLAMS)S10RR028101 · NCRR · VANDERBILT UNIVERSITY · PI ELLACOTT, KATE LJ · 2010 to 2010
$202k
NCRR NIH HHS S10 RR028101NHLBI NIH HHS P01 HL092870NHLBI NIH HHS R01 HL095797NHLBI NIH HHS R01 HL111259NHLBI NIH HHS R01 HL135011NIDDK NIH HHS U24 DK059637
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cav1exerciseinflammationmetabolismmonocytepulmonary hypertension

Identifiers

PMID33015095
PMCPMC7516012
OpenAlexW3086257720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.