Evidence map›Paper›PMID 33015091›Full record

ArticleFrontiers in medicine2020

Evidence of Renal Iron Accumulation in a Male Mouse Model of Lupus.

Lindsey R Theut, Del L Dsouza, Ryan C Grove, Erika I Boesen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Ferroptosis and secondary nephrosis.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024
    Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. The Cross-Link between Ferroptosis and Kidney Diseases.Oxidative medicine and cellular longevity · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lindsey R TheutDepartment of Cellular & Integrative Physiology, University of Nebraska Medical Center, Omaha, NE, United States.
Del L DsouzaDepartment of Cellular & Integrative Physiology, University of Nebraska Medical Center, Omaha, NE, United States.
Ryan C GroveDepartment of Cellular & Integrative Physiology, University of Nebraska Medical Center, Omaha, NE, United States.
Erika I BoesenDepartment of Cellular & Integrative Physiology, University of Nebraska Medical Center, Omaha, NE, United States.
University of Nebraska Medical Center · US

Funding

UNMC Structural Biology CoreP20GM103427 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Heather Colleen Jensen-Smith · 2012 to 2026
$59.2M
NIGMS NIH HHS P20 GM103427
6 · The paper itself

Abstract

Lupus nephritis represents a common and serious complication of the autoimmune disease Systemic Lupus Erythematosus (SLE). Clinical studies suggest that several proteins related to iron metabolism, including transferrin, serve as urinary biomarkers of lupus nephritis. We previously reported that in female NZBWF1 mice, a commonly used mouse model of SLE with a female sex bias, increased urinary transferrin excretion and renal iron accumulation occur around the onset of albuminuria. The current study investigated whether similar findings occur in male mice of a different mouse model of SLE, the MRL/

Indexed as

ironkidneylupustransferrinurine

Identifiers

PMID33015091
PMCPMC7506121
OpenAlexW3083918049

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.