Evidence map›Paper›PMID 33015012›Full record

ArticleFrontiers in bioengineering and biotechnology2020

Bioengineering the Oxygen-Deprived Tumor Microenvironment Within a Three-Dimensional Platform for Studying Tumor-Immune Interactions.

Somshuvra Bhattacharya, Kristin Calar, Claire Evans, Mark Petrasko, Pilar de la Puente

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 36 citations in OpenAlex.

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  13. Organ on Chip Technology to Model Cancer Growth and Metastasis.Bioengineering (Basel, Switzerland) · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Somshuvra BhattacharyaCancer Biology and Immunotherapies Group, Sanford Research, Sioux Falls, SD, United States.
Kristin CalarCancer Biology and Immunotherapies Group, Sanford Research, Sioux Falls, SD, United States.
Claire EvansHistology and Imaging Core, Sanford Research, Sioux Falls, SD, United States.
Mark PetraskoCancer Biology and Immunotherapies Group, Sanford Research, Sioux Falls, SD, United States.
Pilar de la PuenteCancer Biology and Immunotherapies Group, Sanford Research, Sioux Falls, SD, United States.
Sanford Research · USUniversity of South Dakota · US

Funding

The Impact of PD-1 Inhibition on Immune-Response to ChemoradiotherapyP20GM103548 · NIGMS · SANFORD RESEARCH/USD · PI MISKIMINS, W KEITH · 2012 to 2020
$20.8M
NIGMS NIH HHS P20 GM103548
6 · The paper itself

Abstract

Oxygen deprivation within tumors is one of the most prevalent causes of resilient cancer cell survival and increased immune evasion in breast cancer (BCa). Current

Indexed as

bioengineeringbreast cancerimmune evasionoxygen availabilitythree-dimensionaltumor microenvironment

Identifiers

PMID33015012
PMCPMC7498579
OpenAlexW3082587101

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.