Evidence map›Paper›PMID 33014821›Full record

ReviewFrontiers in oncology2020

Clinical Significance of Somatostatin Receptor (SSTR) 2 in Meningioma.

Wei Wu, Yunxiang Zhou, Yali Wang, Lihong Liu, Jianyao Lou, Yongchuan Deng, Peng Zhao, Anwen Shao

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

  1. Pooled it
  2. World journal of nuclear medicine · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. DOTATATE Scan in Meningiomatosis in a Patient With Ophthalmoplegia.Case reports in ophthalmological medicine · 2026
    Article
  7. Combined SSTR2-targeted Analogue withFrontiers in oncology · 2026
    Article
  8. Article
  9. [Oncology letters · 2025
    Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Nuclear medicine and molecular imaging · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Somatostatin and Somatostatin Receptors in Tumour Biology.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Wei WuDepartment of Medical Oncology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Yunxiang ZhouDepartment of Surgical Oncology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Yali WangDepartment of Surgical Oncology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Lihong LiuDepartment of Radiation Oncology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Jianyao LouDepartment of General Surgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Yongchuan DengDepartment of Surgical Oncology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Peng ZhaoDepartment of Medical Oncology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Anwen ShaoDepartment of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Second Affiliated Hospital of Zhejiang University · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Somatostatin receptor (SSTR) 2, widely expressed in meningioma, is a G-protein-coupled receptor and can be activated by somatostatin or its synthetic analogs. SSTR2 is therefore extensively studied as a marker and target for the diagnosis and treatment of meningioma. Accumulating studies have revealed the crucial clinical significance of SSTR2 in meningioma. Summarizing the progress of these studies is urgently needed as it may not only provide novel and better management for patients with meningioma but also indicate the direction of future research. Pertinent literature is reviewed to summarize the recent collective knowledge and understanding of SSTR2's clinical significance in meningioma in this review. SSTR2 offers novel ideas and approaches in the diagnosis, treatment, and prognostic prediction for meningioma, but more and further studies are required.

Indexed as

diagnosismeningiomaprognosissomatostatinsomatostatin analogsSSTR2treatment

Identifiers

PMID33014821
PMCPMC7494964
OpenAlexW3083434041

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.