Evidence map›Paper›PMID 33014820›Full record

ArticleFrontiers in oncology2020

Correlation Patterns Among B7 Family Ligands and Tryptophan Degrading Enzymes in Hepatocellular Carcinoma.

Raghavan Chinnadurai, Rafaela Scandolara, Olatunji B Alese, Dalia Arafat, Deepak Ravindranathan, Alton B Farris, Bassel F El-Rayes, Greg Gibson

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 18 citations in OpenAlex.

  1. Glycosylation of B7-H3 Promotes CD8International journal of biological sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Raghavan ChinnaduraiDepartment of Biomedical Sciences, Mercer University School of Medicine, Savannah, GA, United States.
Rafaela ScandolaraDepartment of Biomedical Sciences, Mercer University School of Medicine, Savannah, GA, United States.
Olatunji B AleseDepartment of Hematology and Oncology, Winship Cancer Institute, Emory University, Atlanta, GA, United States.
Dalia ArafatSchool of Biology, Georgia Institute of Technology, Atlanta, GA, United States.
Deepak RavindranathanDepartment of Hematology and Oncology, Winship Cancer Institute, Emory University, Atlanta, GA, United States.
Alton B FarrisDepartment of Pathology and Laboratory Medicine, Emory University, Atlanta, GA, United States.
Bassel F El-RayesDepartment of Hematology and Oncology, Winship Cancer Institute, Emory University, Atlanta, GA, United States.
Greg GibsonSchool of Biology, Georgia Institute of Technology, Atlanta, GA, United States.
Emory University · USGeorgia Institute of Technology · USMercer University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mechanisms of dysfunctional T cell immunity in Hepatocellular Carcinoma (HCC) need to be well defined. B7 family molecules provide both co-stimulatory and co-inhibitory signals to T cells while tryptophan degrading enzymes like Indoleamine 2,3 dioxygenase (IDO) and Tryptophan 2,3 Dioxygenase (TDO) mediate tumor immune tolerance. It is necessary to identify their

Indexed as

B7 family moleculesco-inhibitionco-stimulationhepatocellular carcinomaindoleamine 2,3 dioxygenasePD-L1T cell immunity

Identifiers

PMID33014820
PMCPMC7494748
OpenAlexW3083515877

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.