Evidence map›Paper›PMID 33014612›Full record

ArticleBiomedical optics express2020

AV-Net: deep learning for fully automated artery-vein classification in optical coherence tomography angiography.

Minhaj Alam, David Le, Taeyoon Son, Jennifer I Lim, Xincheng Yao

Abstract read
In one paragraph

Article in Biomedical optics express, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
  2. Article
  3. OCTA-ReVABiomedical optics express · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Advances in OCT Angiography.Translational vision science & technology · 2025
    Review
  8. Article
  9. OCTA-based AMD Stage Grading Enhancement via Class-Conditioned Style Transfer.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2024
    Article
  10. Article
  11. Review
  12. Robust AMD Stage Grading with Exclusively OCTA Modality Leveraging 3D Volume.... IEEE International Conference on Computer Vision workshops. IEEE International Conference on Computer Vision · 2023
    Article
  13. Review
  14. Article
  15. Cardiac Adipose Tissue Segmentation via Image-Level Annotations.IEEE journal of biomedical and health informatics · 2023
    Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Minhaj AlamDepartment of Bioengineering, University of Illinois at Chicago, Chicago, IL 60607, USA.ORCID https://orcid.org/0000-0003-3095-2232
David LeDepartment of Bioengineering, University of Illinois at Chicago, Chicago, IL 60607, USA.
Taeyoon SonDepartment of Bioengineering, University of Illinois at Chicago, Chicago, IL 60607, USA.
Jennifer I LimDepartment of Bioengineering, University of Illinois at Chicago, Chicago, IL 60607, USA.
Xincheng YaoDepartment of Bioengineering, University of Illinois at Chicago, Chicago, IL 60607, USA.ORCID https://orcid.org/0000-0002-0356-3242

Funding

Translational Core for Therapeutic and Diagnostic DevelopmentP30EY001792 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MCANANY, JAMES JASON · 1985 to 2025
$14.8M
Functional imaging of retinal photoreceptorsR01EY023522 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI YAO, XINCHENG · 2014 to 2024
$3.5M
Nonmydriatic ultra-widefield fundus photography employing trans-pars-planar illuminationR01EY029673 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CHAN, ROBISON VERNON PAUL, YAO, XINCHENG · 2019 to 2022
$1.8M
Differential artery-vein analysis in OCT angiography for objective classification of diabetic retinopathyR01EY030842 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LIM, JENNIFER IRENE, YAO, XINCHENG · 2020 to 2023
$1.7M
Functional tomography of neurovascular coupling interactions in healthy and diseased retinasR01EY030101 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI YAO, XINCHENG · 2019 to 2022
$1.4M
NEI NIH HHS P30 EY001792NEI NIH HHS R01 EY023522NEI NIH HHS R01 EY029673NEI NIH HHS R01 EY030101NEI NIH HHS R01 EY030842
6 · The paper itself

Abstract

This study is to demonstrate deep learning for automated artery-vein (AV) classification in optical coherence tomography angiography (OCTA). The AV-Net, a fully convolutional network (FCN) based on modified U-shaped CNN architecture, incorporates enface OCT and OCTA to differentiate arteries and veins. For the multi-modal training process, the enface OCT works as a near infrared fundus image to provide vessel intensity profiles, and the OCTA contains blood flow strength and vessel geometry features. A transfer learning process is also integrated to compensate for the limitation of available dataset size of OCTA, which is a relatively new imaging modality. By providing an average accuracy of 86.75%, the AV-Net promises a fully automated platform to foster clinical deployment of differential AV analysis in OCTA.

Identifiers

PMID33014612
PMCPMC7510886

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.