Evidence map›Paper›PMID 33014586›Full record

ArticleBiomedical optics express2020

HER2 biosensing through SPR-envelope tracking in plasmonic optical fiber gratings.

Maxime Lobry, Médéric Loyez, Karima Chah, Eman M Hassan, Erik Goormaghtigh, Maria C DeRosa, Ruddy Wattiez, Christophe Caucheteur

Abstract read
In one paragraph

Article in Biomedical optics express, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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  12. Flexible Sensing Systems for Cancer Diagnostics.Advances in experimental medicine and biology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Maxime LobryElectromagnetism and Telecommunication Department, University of Mons, 31 Bld Dolez, 7000 Mons, Belgium.ORCID https://orcid.org/0000-0003-0876-8711
Médéric LoyezProteomics and Microbiology Department, University of Mons, 6 Av. du Champ de Mars, 7000 Mons, Belgium.
Karima ChahElectromagnetism and Telecommunication Department, University of Mons, 31 Bld Dolez, 7000 Mons, Belgium.
Eman M HassanInstitute of Biochemistry, Carleton University, 1125 Colonel By Drive, Ottawa, Ontario, K1S 5B6, Canada.
Erik GoormaghtighLaboratory for the Structure and Function of Biological Membranes, Center for Structural Biology and Bioinformatics, Université Libre de Bruxelles, Bld du Triomphe 2,1050 Brussels, Belgium.
Maria C DeRosaInstitute of Biochemistry, Carleton University, 1125 Colonel By Drive, Ottawa, Ontario, K1S 5B6, Canada.
Ruddy WattiezProteomics and Microbiology Department, University of Mons, 6 Av. du Champ de Mars, 7000 Mons, Belgium.
Christophe CaucheteurElectromagnetism and Telecommunication Department, University of Mons, 31 Bld Dolez, 7000 Mons, Belgium.ORCID https://orcid.org/0000-0002-6453-6790

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the biomedical detection context, plasmonic tilted fiber Bragg gratings (TFBGs) have been demonstrated to be a very accurate and sensitive sensing tool, especially well-adapted for biochemical detection. In this work, we have developed an aptasensor following a triple strategy to improve the overall sensing performances and robustness. Single polarization fiber (SPF) is used as biosensor substrate while the demodulation is based on tracking a peculiar feature of the lower envelope of the cladding mode resonances spectrum. This method is highly sensitive and yields wavelength shifts several tens of times higher than the ones reported so far based on the tracking of individual modes of the spectrum. An amplification of the response is further performed through a sandwich assay by the use of specific antibodies. These improvements have been achieved on a biosensor developed for the detection of the HER2 (

Identifiers

PMID33014586
PMCPMC7510885

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.