ArticleBiomedical optics express2020
Application of the generalized contrast-to-noise ratio to assess photoacoustic image quality.
Article in Biomedical optics express, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed, 90 citations in OpenAlex.
- Monte Carlo-Based Optimization of Multi-Source Illumination for Photoacoustic Signal Generation in Human Gray-Matter Vessels.Journal of biophotonics · 2026Article
- Real-time photoacoustic imaging with freehand light delivery and augmented reality guidance.Photoacoustics · 2026Article
- Assessing image quality in photoacoustic imaging: A metric-based and deep learning-based evaluation.Photoacoustics · 2026Article
- Fetal monitoring for high-risk pregnancies using a wearable ultrasound patch.Nature biotechnology · 2026Article
- Fast 3D dynamic visualization of porcine spermatozoa by using high-resolution wavefront coding light sheet microscopy and machine learning.Scientific reports · 2026Article
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- Advances in photoacoustic imaging reconstruction and quantitative analysis for biomedical applications.Visual computing for industry, biomedicine, and art · 2026Review
- Reduction of photobleaching effects in photoacoustic imaging using noise agnostic, platform-flexible deep-learning methods.Journal of biomedical optics · 2025Article
- Fetal monitoring using a wearable ultrasound patch for high-risk pregnancies.Research square · 2025Article
- Artifacts in photoacoustic imaging: Origins and mitigations.Photoacoustics · 2025Article
- Null subtraction imaging combined with modified delay multiply-and-sum beamforming for coherent plane-wave compounding.Medical & biological engineering & computing · 2025Article
- Spectroscopic photoacoustic denoising framework using hybrid analytical and data-free learning method.Photoacoustics · 2025Article
- Motion-based dynamic light delivery to minimize laser-related thermal damage while preserving photoacoustic image quality.Journal of biomedical optics · 2025Article
- Enhanced clinical photoacoustic vascular imaging through a skin localization network and adaptive weighting.Photoacoustics · 2025Article
- An in-silico simulation study to generate computed tomography images from ultrasound data by using deep learning techniques.BJR artificial intelligence · 2025Article
- Comparison of Filtering Methods for Calculating ARFI log(VoA) to Delineate Carotid Plaque Features, In Vivo.IEEE open journal of ultrasonics, ferroelectrics, and frequency control · 2025Article
- Article
- Impact of skin tone on target size detectability in photoacoustic breast imaging.Biophotonics discovery · 2024Article
- Extractor-attention-predictor network for quantitative photoacoustic tomography.Photoacoustics · 2024Article
- On the Importance of Low-Frequency Signals in Functional and Molecular Photoacoustic Computed Tomography.IEEE transactions on medical imaging · 2024Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The generalized contrast-to-noise ratio (gCNR) is a relatively new image quality metric designed to assess the probability of lesion detectability in ultrasound images. Although gCNR was initially demonstrated with ultrasound images, the metric is theoretically applicable to multiple types of medical images. In this paper, the applicability of gCNR to photoacoustic images is investigated. The gCNR was computed for both simulated and experimental photoacoustic images generated by amplitude-based (i.e., delay-and-sum) and coherence-based (i.e., short-lag spatial coherence) beamformers. These gCNR measurements were compared to three more traditional image quality metrics (i.e., contrast, contrast-to-noise ratio, and signal-to-noise ratio) applied to the same datasets. An increase in qualitative target visibility generally corresponded with increased gCNR. In addition, gCNR magnitude was more directly related to the separability of photoacoustic signals from their background, which degraded with the presence of limited bandwidth artifacts and increased levels of channel noise. At high gCNR values (i.e., 0.95-1), contrast, contrast-to-noise ratio, and signal-to-noise ratio varied by up to 23.7-56.2 dB, 2.0-3.4, and 26.5-7.6×10
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.