Evidence map›Paper›PMID 33014554›Full record

ArticleBiomedical optics express2020

Investigation of non-uniformly emitting optical fiber diffusers on the light distribution in tissue.

Stephan Ströbl, Matthias Domke, Adrian Rühm, Ronald Sroka

Abstract read
In one paragraph

Article in Biomedical optics express, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Stephan StröblResearch Centre for Microtechnology, FH Vorarlberg, Dornbirn, Vorarlberg, Austria.
Matthias DomkeResearch Centre for Microtechnology, FH Vorarlberg, Dornbirn, Vorarlberg, Austria.
Adrian RühmLaser Research Laboratory, LIFE Centre, LMU Munich, Bavaria, Germany.
Ronald SrokaLaser Research Laboratory, LIFE Centre, LMU Munich, Bavaria, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The influence of inhomogeneities in the emission characteristics of optical fiber diffusers on the light distribution within biological tissue was evaluated by Monte Carlo (MC) simulations and by experiments on optical phantoms. Due to the strong scattering of light within biological tissue, inhomogeneities in the emission profile become blurred within a short light propagation distance, so that the light distribution within the tissue approaches that of a homogeneous diffuser. The degree of feature vanishing in the light distribution is mainly determined by the width of the inhomogeneities. It was shown that the influence of local inhomogeneities on top of a homogeneous light distribution fades away very effectively within 1 mm of tissue depth, which results in a light distribution very close to that for a homogeneously emitting diffuser. Emission profiles composed of multiple narrow peaks distributed over the full diffuser length with a peak-to-peak distance of less than 2 mm result in an almost homogeneous light distribution after approximately 1 mm of tissue depth. While this article is focused on the impact of diffuser inhomogeneities on the light distribution within the tissue, the importance of further investigations on the related thermal effects is also discussed.

Identifiers

PMID33014554
PMCPMC7510903

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.