Evidence map›Paper›PMID 33014551›Full record

ArticleBiomedical optics express2020

Pitch-rotational manipulation of single cells and particles using single-beam thermo-optical tweezers.

Sumeet Kumar, M Gunaseelan, Rahul Vaippully, Amrendra Kumar, Mithun Ajith, Gaurav Vaidya, Soumya Dutta, Basudev Roy

Abstract read
In one paragraph

Article in Biomedical optics express, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Thermo-optical tweezers based on photothermal waveguides.Microsystems & nanoengineering · 2024
    Article
  2. Article
  3. Article
  4. Optothermal rotation of micro-/nano-objects.Chemical communications (Cambridge, England) · 2023
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Heat-Mediated Optical Manipulation.Chemical reviews · 2022
    Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sumeet KumarDepartment of Physics, Indian Institute of Technology Madras, Chennai, 600036, India.
M GunaseelanDepartment of Physics, Indian Institute of Technology Madras, Chennai, 600036, India.
Rahul VaippullyDepartment of Physics, Indian Institute of Technology Madras, Chennai, 600036, India.
Amrendra KumarDepartment of Physics, Indian Institute of Technology Madras, Chennai, 600036, India.
Mithun AjithDepartment of Electrical Engineering, Indian Institute of Technology Madras, Chennai, 600036, India.
Gaurav VaidyaDepartment of Physics, Indian Institute of Technology Madras, Chennai, 600036, India.
Soumya DuttaDepartment of Electrical Engineering, Indian Institute of Technology Madras, Chennai, 600036, India.
Basudev RoyDepartment of Physics, Indian Institute of Technology Madras, Chennai, 600036, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

3D pitch rotation of microparticles and cells assumes importance in a wide variety of applications in biology, physics, chemistry and medicine. Applications such as cell imaging and injection benefit from pitch-rotational manipulation. Generation of such motion in single beam optical tweezers has remained elusive due to the complexities of generating high enough ellipticity perpendicular to the direction of propagation. Further, trapping a perfectly spherical object at two locations and subsequent pitch rotation hasn't yet been demonstrated to be possible. Here, we use hexagonal-shaped upconverting particles and single cells trapped close to a gold-coated glass cover slip in a sample chamber to generate complete 360 degree and continuous pitch motion even with a single optical tweezer beam. The tweezers beam passing through the gold surface is partially absorbed and generates a hot-spot to produce circulatory convective flows in the vicinity which rotates the objects. The rotation rate can be controlled by the intensity of the laser light. Thus such a simple configuration can turn the particle in the pitch sense. The circulatory flows in this technique have a diameter of about 5

Identifiers

PMID33014551
PMCPMC7510922

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.