Evidence map›Paper›PMID 33014546›Full record

ArticleBiomedical optics express2020

Fiber photometry for monitoring cerebral oxygen saturation in freely-moving rodents.

Linhui Yu, Elizabeth M S Thurston, Mada Hashem, Jeff F Dunn, Patrick J Whelan, Kartikeya Murari

Abstract read
In one paragraph

Article in Biomedical optics express, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. The relationship between cytochrome c oxidase, CBF and CMROJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Linhui YuUniversity of Calgary, Schulich School of Engineering, Electrical and Computer Engineering, Calgary, Canada.ORCID https://orcid.org/0000-0001-6290-9867
Elizabeth M S ThurstonUniversity of Calgary, Hotchkiss Brain Institute, Calgary, Canada.
Mada HashemUniversity of Calgary, Hotchkiss Brain Institute, Calgary, Canada.
Jeff F DunnUniversity of Calgary, Hotchkiss Brain Institute, Calgary, Canada.
Patrick J WhelanUniversity of Calgary, Hotchkiss Brain Institute, Calgary, Canada.
Kartikeya MurariUniversity of Calgary, Schulich School of Engineering, Electrical and Computer Engineering, Calgary, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemodynamic parameters, such as tissue oxygen saturation and blood volume fraction, are important markers of brain physiology. They are also widely used surrogate markers of electrophysiological activity. Here, we present a single fiber spectroscopic (SFS) system for monitoring cerebral oxygen saturation in localized, non-line-of-sight brain regions in freely-moving rodents. We adapted the implantation ferrule and patch cable design from commercialized optogenetics and fiber photometry systems, enabling stereotaxic fiber implantation, longitudinal tissue access and measurement from freely-moving animals. The optical system delivers and collects light from the brain through a 200

Identifiers

PMID33014546
PMCPMC7510909

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.