Evidence map›Paper›PMID 33014545›Full record

ArticleBiomedical optics express2020

Dual wavelength spread-spectrum time-resolved diffuse optical instrument for the measurement of human brain functional responses.

Konstantinos I Papadimitriou, Ernesto E Vidal Rosas, Edward Zhang, Robert J Cooper, Jeremy C Hebden, Simon R Arridge, Samuel Powell

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Konstantinos I PapadimitriouDepartment of Computer Science, University College London, London, WC1E 6BT, UK.ORCID https://orcid.org/0000-0002-0995-4834
Ernesto E Vidal RosasDepartment of Medical Physics and Biomedical Engineering, University College London, London, WC1E 6BT, UK.
Edward ZhangDepartment of Medical Physics and Biomedical Engineering, University College London, London, WC1E 6BT, UK.
Robert J CooperDepartment of Medical Physics and Biomedical Engineering, University College London, London, WC1E 6BT, UK.
Jeremy C HebdenDepartment of Medical Physics and Biomedical Engineering, University College London, London, WC1E 6BT, UK.
Simon R ArridgeDepartment of Computer Science, University College London, London, WC1E 6BT, UK.
Samuel PowellFaculty of Engineering, University of Nottingham, Nottingham, NG7 2RD, UK.ORCID https://orcid.org/0000-0003-0397-5121
University College London · GBUniversity of Nottingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Near-infrared spectroscopy has proven to be a valuable method to monitor tissue oxygenation and haemodynamics non-invasively and in real-time. Quantification of such parameters requires measurements of the time-of-flight of light through tissue, typically achieved using picosecond pulsed lasers, with their associated cost, complexity, and size. In this work, we present an alternative approach that employs spread-spectrum excitation to enable the development of a small, low-cost, dual-wavelength system using vertical-cavity surface-emitting lasers. Since the optimal wavelengths and drive parameters for optical spectroscopy are not served by commercially available modules as used in our previous single-wavelength demonstration platform, we detail the design of a custom instrument and demonstrate its performance in resolving haemodynamic changes in human subjects during apnoea and cognitive task experiments.

Identifiers

PMID33014545
PMCPMC7510926
OpenAlexW3022203780

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.