Evidence map›Paper›PMID 33014435›Full record

ArticleNPJ vaccines2020

Induction of protection in mice against a respiratory challenge by a vaccine formulated with exosomes isolated from

Sukumar Pal, Yeva Mirzakhanyan, Paul Gershon, Delia F Tifrea, Luis M de la Maza

Open access · goldAbstract read
In one paragraph

Article in NPJ vaccines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Immunomodulatory properties ofFrontiers in parasitology · 2024
    Article
  4. Article
  5. Article
  6. Expert review of vaccines · 2021
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sukumar PalDepartment of Pathology and Laboratory Medicine, University of California, Irvine, Irvine, CA USA.
Yeva MirzakhanyanDepartment of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, CA USA.
Paul GershonDepartment of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, CA USA.
Delia F TifreaDepartment of Pathology and Laboratory Medicine, University of California, Irvine, Irvine, CA USA.
Luis M de la MazaDepartment of Pathology and Laboratory Medicine, University of California, Irvine, Irvine, CA USA.
University of California, Irvine · USIrvine University · US

Funding

Trapping membrane proteins with adjuvant-carrying amphipols for vaccine formulatiR01AI092129 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI COCCO, MELANIE J, DE LA MAZA, LUIS M · 2011 to 2014
$1.3M
LTQ Velos Pro mass spectrometer with ETD and other optionsS10OD016328 · OD · UNIVERSITY OF CALIFORNIA-IRVINE · PI GERSHON, PAUL D · 2013 to 2013
$374k
NIAID NIH HHS R01 AI092129NIH HHS S10 OD016328
6 · The paper itself

Abstract

The goal of this study was to determine if exosomes, isolated from

Indexed as

Infectious diseasesProtein vaccinesVaccines

Identifiers

PMID33014435
PMCPMC7501220
OpenAlexW3090282256

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.