Evidence map›Paper›PMID 33014430›Full record

ArticleCell death discovery2020

EDIL3 promotes epithelial-mesenchymal transition and paclitaxel resistance through its interaction with integrin α

J Gasca, M L Flores, R Jiménez-Guerrero, M E Sáez, I Barragán, M Ruíz-Borrego, M Tortolero, F Romero, C Sáez, M A Japón

Open access · goldAbstract read
In one paragraph

Article in Cell death discovery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 61 citations in OpenAlex.

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  11. The functional role of the extracellular matrix in inflammatory bowel disease associated gut fibrosis.Matrix biology : journal of the International Society for Matrix Biology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

J Gasca *Instituto de Biomedicina de Sevilla (IBIS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, 41013 Seville, Spain.ORCID 0000-0002-5955-6148
M L Flores *Instituto de Biomedicina de Sevilla (IBIS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, 41013 Seville, Spain.
R Jiménez-GuerreroInstituto de Biomedicina de Sevilla (IBIS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, 41013 Seville, Spain.ORCID 0000-0003-4237-6236
M E SáezCentro Andaluz de Estudios Bioinformáticos (CAEBi), 41013 Seville, Spain.ORCID 0000-0001-9299-2534
I BarragánDepartment of Physiology and Pharmacology, Karolinska Institutet, 17177 Stockholm, Sweden.ORCID 0000-0002-8586-6502
M Ruíz-BorregoDepartment of Medical Oncology, Hospital Universitario Virgen del Rocío, 41013 Seville, Spain.
M TortoleroDepartment of Microbiology, Faculty of Biology, Universidad de Sevilla, 41012 Seville, Spain.
F RomeroDepartment of Microbiology, Faculty of Biology, Universidad de Sevilla, 41012 Seville, Spain.ORCID 0000-0002-9588-6881
C SáezInstituto de Biomedicina de Sevilla (IBIS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, 41013 Seville, Spain.ORCID 0000-0002-8600-0508
M A JapónInstituto de Biomedicina de Sevilla (IBIS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, 41013 Seville, Spain.ORCID 0000-0002-5980-5044
Instituto de Biomedicina de Sevilla · ESUniversidad de Sevilla · ESCentro Andaluz de Biología del Desarrollo · ESHospital Universitario Virgen del Rocío · ESKarolinska Institutet · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epithelial-mesenchymal transition (EMT) has recently been associated with tumor progression, metastasis, and chemotherapy resistance in several tumor types. We performed a differential gene expression analysis comparing paclitaxel-resistant vs. paclitaxel-sensitive breast cancer cells that showed the upregulation of

Indexed as

OncogenesisPrognostic markersTranslational research

Identifiers

PMID33014430
PMCPMC7494865
OpenAlexW3088086152

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.