ArticleTherapeutic advances in infectious disease
Evaluating appropriateness and diagnostic stewardship opportunities of multiplex polymerase chain reaction gastrointestinal testing within a hospital system.
Article in Therapeutic advances in infectious disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 23 citations in OpenAlex.
- Association Between Weather Variables and Viral Gastroenteritis in the United States.Open forum infectious diseases · 2026Article
- Impact of the BioFireBMC infectious diseases · 2026Article
- Derivation and validation of clinical prediction models for viral etiologies of acute diarrhea in North American children presenting for emergency care.medRxiv : the preprint server for health sciences · 2026Article
- Repeat multiplex PCR gastrointestinal panel testing within 14 days yields minimal additional diagnostic information: a multicenter cohort study.Infection control and hospital epidemiology · 2026Article
- Association between Weather Variables and Viral Gastroenteritis in the United States.medRxiv : the preprint server for health sciences · 2026Article
- Detection and assessment of fecal carriage of gastrointestinal pathogens in healthy community adults: a year-long study.BMC infectious diseases · 2026Article
- Overuse of a molecular infectious diarrhea panel in acute care: an opportunity for diagnostic stewardship.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026Article
- Multiplex Polymerase Chain Reaction Panels for Gastrointestinal Infections: Current Evidence, Regulatory Hurdles, and the Way Forward.Open forum infectious diseases · 2025Article
- Parent and Clinician Perspectives on Diagnostic Testing for Children With Diarrhea: A Qualitative Study.JAMA network open · 2025Article
- Multicenter evaluation of the QIAstat-Dx Gastrointestinal Panel 2, a multiplex PCR platform for the diagnosis of acute gastroenteritis.Journal of clinical microbiology · 2025Article
- Antimicrobial changes made for suspected infectious diarrhea after positive gastrointestinal pathogen panel result.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- Clinical decision support for gastrointestinal panel testing.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2024Article
- Rapid diagnostics to enhance therapy selection for the treatment of bacterial infections.Current pharmacology reports · 2023Article
- Diagnostic stewardship to limit repeat plasma cytomegalovirus viral load testing.BMC infectious diseases · 2023Article
- The Impact of a Positive BiofireDiagnostics (Basel, Switzerland) · 2023Article
- Is the Medium Still the Message? Culture-Independent Diagnosis of Gastrointestinal Infections.Digestive diseases and sciences · 2022Review
- Verification of analytical bacterial spectrum of QIAstat-Dx® GI V2 and Novodiag® Bacterial GE+ V2-0 diagnostic panels.The Journal of antimicrobial chemotherapy · 2021Article
- The effect of gastrointestinal pathogen panel (GIP) on antibiotic management.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2021Article
- Approach to fever in patients with neutropenia: a review of diagnosis and management.Therapeutic advances in infectious diseaseReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis single-center, retrospective, observational cohort study evaluates the appropriateness of the BioFire® FilmArray® Gastrointestinal (GI) multiplex PCR panel testing at a community-teaching hospital.
methodsAll adult, hospitalized patients at Prisma Health Richland Hospital with a documented GI multiplex PCR panel from 1 April 2015 through 28 February 2018 were included in the analysis. Inappropriate use of the GI panel was defined as a test obtained without documented diarrhea, greater than 2 days of hospitalization, redundant use with other diagnostic tests (e.g.
resultsDuring the study period, 442 GI panels were obtained, among which 268 (61%) were deemed inappropriate. Primary reasons for inappropriate testing were lack of documented diarrhea (
conclusionStewardship opportunities exist to optimize the diagnostic application of the GI multiplex PCR panel.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.