Evidence map›Paper›PMID 33014330›Full record

ArticleTherapeutic advances in drug safety2020

Effects of stratified medication review in high-risk patients at admission to hospital: a randomised controlled trial.

Dorthe Krogsgaard Bonnerup, Marianne Lisby, Eva Aggerholm Sædder, Birgitte Brock, Tania Truelshøj, Charlotte Arp Sørensen, Anita Gorm Pedersen, Lars Peter Nielsen

Abstract read
In one paragraph

Article in Therapeutic advances in drug safety, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dorthe Krogsgaard BonnerupHospital Pharmacy, Central Denmark Region, Randers Regional Hospital, Dronningborg Boulevard 16D, DK-8930 Randers NØ, Denmark.ORCID https://orcid.org/0000-0002-8246-4372
Marianne LisbyResearch Centre for Emergency Medicine, Aarhus University Hospital, Denmark.
Eva Aggerholm SædderDepartment of Clinical Pharmacology, Aarhus University Hospital, Denmark.
Birgitte BrockDepartment of Clinical Biochemistry, Aarhus University Hospital, Denmark.
Tania TruelshøjHospital Pharmacy, Central Denmark Region, Denmark.
Charlotte Arp SørensenHospital Pharmacy, Central Denmark Region, Denmark.
Anita Gorm PedersenHospital Pharmacy, Central Denmark Region, Denmark.
Lars Peter NielsenDepartment of Clinical Pharmacology, Aarhus University Hospital, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients at high risk of medication errors will potentially benefit most from medication reviews. An algorithm, MERIS, can identify the patients who are at highest risk of medication errors. The aim of this study was to examine the effects of performing stratified medication reviews on patients who according to MERIS were at highest risk of medication errors.

methodsA randomised controlled trial was performed at the Acute Admissions Unit, Aarhus University Hospital, Denmark. Patients were included at admission to the hospital and were randomised to control or intervention. The intervention consisted of stratified medication review at admission on patients with a high MERIS score. Clinical pharmacists and clinical pharmacologists performed the medication reviews; the clinical pharmacologists performed the reviews on patients with the highest MERIS score. The primary outcome measure was the number of prescribing errors during the hospitalisation. Secondary outcomes included self-experienced quality of life, health-care utilisation and mortality measured at follow-up 90 days after discharge.

resultsA total of 375 patients were included, of which medication reviews were performed in 64 patients. The medication reviews addressed 63 prescribing errors in 37 patients and 60 other drug-related problems. No difference in the number of prescribing errors during hospitalisation between the intervention group (

conclusionA stratified medication review approach based on the individual patient's risk of medication errors did not show impact on the chosen outcomes. PLAIN LANGUAGE SUMMARY:

Indexed as

medication errorsmedication reviewrandomised controlled trial

Identifiers

PMID33014330
PMCPMC7509721

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