Evidence map›Paper›PMID 33014311›Full record

ArticleJournal of oral microbiology2020

Incidence of infective endocarditis caused by viridans group streptococci in Sweden - effect of cessation of antibiotic prophylaxis in dentistry for risk individuals.

Niko Vähäsarja, Bodil Lund, Anders Ternhag, Bengt Götrick, Lars Olaison, Margareta Hultin, Carina Krüger Weiner, Aron Naimi-Akbar

Open access · goldAbstract read
In one paragraph

Article in Journal of oral microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Endocarditis prevention: time for a review of NICE guidance.The Lancet regional health. Europe · 2024
    Review
  8. Article
  9. Article
  10. Infective Endocarditis Among High-risk Individuals Before and After the Cessation of Antibiotic Prophylaxis in Dentistry: A National Cohort Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Article
  11. Pediatric Infective Endocarditis: A Literature Review.Journal of clinical medicine · 2022
    Review
  12. Article
  13. Wissen kompakt : Fortbildung fur Zahnarzte · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Niko VähäsarjaDepartment of Dental Medicine, Karolinska Institutet, Huddinge, Sweden.ORCID https://orcid.org/0000-0002-4974-484X
Bodil LundDepartment of Dental Medicine, Karolinska Institutet, Huddinge, Sweden.
Anders TernhagDepartment of Medicine Solna, Karolinska Institutet, Unit for Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden.
Bengt GötrickDepartment of Oral Diagnostics Faculty of Odontology, Malmö University, Malmö, Sweden.
Lars OlaisonDepartment of Infectious Diseases, Institute of Biomedicine, Sahlgrenska University Hospital, Sweden.
Margareta HultinDepartment of Dental Medicine, Karolinska Institutet, Huddinge, Sweden.
Carina Krüger WeinerDepartment of Dental Medicine, Karolinska Institutet, Huddinge, Sweden.
Aron Naimi-AkbarDepartment of Dental Medicine, Karolinska Institutet, Huddinge, Sweden.
Karolinska Institutet · SEMalmö University · SEHaukeland University Hospital · NOKarolinska University Hospital · SESahlgrenska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn October 2012, the Swedish Medical Products Agency published new recommendations for the cessation of prophylactic antibiotics in dentistry for the prevention of infective endocarditis (IE). Previously, 2 g of amoxicillin per os would be administered 1 h before invasive dental procedures to patients with valve prosthesis, complicated heart valve disease, and to those with previous endocarditis.

objectivesThe aim of this study was to evaluate whether the total incidence of IE caused by oral viridans group streptococci (VGS) or IE caused by staphylococci, increased in Sweden after the introduction of the new recommendations.

methodsThe incidence of IE in Sweden before and after October 2012 was calculated and compared using an interrupted time series analysis. Separate analyses were conducted for the total incidence of IE, and IE caused by VGS or

resultsThe results show no statistically significant increase in the slope of the trend line of the total incidence of IE, IE caused by VGS or

conclusionThe results suggest that the recommended cessation of prophylactic antibiotics for the prevention of IE in dentistry has not led to an increased incidence of IE caused by oral streptococci among the Swedish population.

Indexed as

dentistryinfective endocarditisProphylactic antibioticsviridans group streptococci

Identifiers

PMID33014311
PMCPMC7520904
OpenAlexW3026352484

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.