Evidence map›Paper›PMID 33014269›Full record

ArticleOxidative medicine and cellular longevity2020

Identification of Six Flavonoids as Novel Cellular Antioxidants and Their Structure-Activity Relationship.

Qiang Zhang, Wenbo Yang, Jiechao Liu, Hui Liu, Zhenzhen Lv, Chunling Zhang, Dalei Chen, Zhonggao Jiao

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 79 citations in OpenAlex.

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  16. Total Flavonoids inInternational journal of molecular sciences · 2023
    Article
  17. Article
  18. Article
  19. Flavonoid Composition and Antioxidant Activity ofPlants (Basel, Switzerland) · 2023
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Qiang ZhangZhengzhou Fruit Research Institute, Chinese Academy of Agricultural Sciences, Zhengzhou, 450009 Henan, China.ORCID https://orcid.org/0000-0002-5247-8992
Wenbo YangZhengzhou Fruit Research Institute, Chinese Academy of Agricultural Sciences, Zhengzhou, 450009 Henan, China.
Jiechao LiuZhengzhou Fruit Research Institute, Chinese Academy of Agricultural Sciences, Zhengzhou, 450009 Henan, China.
Hui LiuZhengzhou Fruit Research Institute, Chinese Academy of Agricultural Sciences, Zhengzhou, 450009 Henan, China.
Zhenzhen LvZhengzhou Fruit Research Institute, Chinese Academy of Agricultural Sciences, Zhengzhou, 450009 Henan, China.
Chunling ZhangZhengzhou Fruit Research Institute, Chinese Academy of Agricultural Sciences, Zhengzhou, 450009 Henan, China.
Dalei ChenZhengzhou Fruit Research Institute, Chinese Academy of Agricultural Sciences, Zhengzhou, 450009 Henan, China.
Zhonggao JiaoZhengzhou Fruit Research Institute, Chinese Academy of Agricultural Sciences, Zhengzhou, 450009 Henan, China.ORCID https://orcid.org/0000-0002-2439-7706
Zhengzhou Fruit Research Institute · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study is aimed at determining the relationship of flavonoid structures to their chemical and intracellular antioxidant activities. The antioxidant activities of 60 flavonoids were investigated by three different antioxidant assays, including 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity, oxygen radical absorption capacity (ORAC), and cellular antioxidant activity (CAA) assays. The result showed 6 flavonoids as good cellular antioxidants evaluated for the first time. The cellular antioxidant activities of compounds 7-methoxy-quercetin, 3-

Indexed as

AntioxidantsCatalaseCell ProliferationFlavonoidsHep G2 CellsHumansKaempferolsQuercetinStructure-Activity RelationshipSuperoxide DismutaseUp-Regulation3-methylquercetinAntioxidantsCatalaseFlavonoidskaempferolKaempferolsQuercetinrhamnetinSuperoxide Dismutase

Identifiers

PMID33014269
PMCPMC7525318
OpenAlexW3088091345

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.