SynthesisPain research & management2020
Efficacy and Safety of Ultrasound-Guided Radiofrequency Treatment for Chronic Pain in Patients with Knee Osteoarthritis: A Systematic Review and Meta-Analysis.
Synthesis in Pain research & management, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 36 citations in OpenAlex.
- Comparison of extracorporeal shock wave therapy and high-intensity laser therapy on pain, grip strength, and function in patients with lateral epicondylalgia: a randomized controlled study.Lasers in medical science · 2022Trial
- Percutaneous denervation for the treatment of knee pain.Skeletal radiology · 2026Review
- Osteoarthritis: Epidemiology, Diagnosis, and Treatment.MedComm · 2026Review
- Improved Sleep Associated With Triamcinolone Acetonide Extended-Release Injections for Knee Osteoarthritis: Use of a New Real-World Registry.Arthroplasty today · 2025Article
- Association of Knee Osteoarthritis Treatment Types, Patient Characteristics, and Medical History With Subsequent Risk for Total Knee Arthroplasty: Data From a New Real-World Registry.Arthroplasty today · 2025Article
- Review
- 9. Chronic knee pain.Pain practice : the official journal of World Institute of Pain · 2025Review
- Genicular nerve radiofrequency ablation: proposal of a technical protocol for managing procedural pain.The Korean journal of pain · 2025Article
- Radiofrequency for Chronic Knee Pain: A Literature Review.Journal of pain research · 2025Review
- The Impact of Patient-Controlled Analgesia Combined with Self-Management Training on Pain Modulation in Diabetic Patients with Chronic Knee Pain.Journal of pain research · 2025Article
- Ultrasound guided procedures in the musculoskeletal system: a narrative review with illustrative examples.Quantitative imaging in medicine and surgery · 2024Review
- A retrospective assessment of the effectiveness of pulsed radiofrequency ablation in the treatment of chronic pain caused by advanced knee osteoarthritis.Anaesthesiology intensive therapy · 2024Article
- An alternative treatment option in older adults with knee osteoarthritis : Genicular nerve pulsed radiofrequency.Wiener klinische Wochenschrift · 2023Article
- THERAPEUTIC GENICULAR NERVE BLOCK FOR CHRONIC PAIN MANAGEMENT IN PATIENTS WITH KNEE OSTEOARTHRITIS.Acta clinica Croatica · 2023Article
- Article
- Lateral Gradual Opening Osteotomy of the Tibia With Monolateral External Fixator for Correcting the Valgus Deformity of the Tibia.Arthroscopy techniques · 2022Article
- Predictive factors associated with successful response to utrasound guided genicular radiofrequency ablation.The Korean journal of pain · 2022Article
- Feasibility study of ultrasound-guided percutaneous laser discectomy for cervical radicular pain.Scientific reports · 2022Article
- Genicular nerve radiofrequency ablation for pain control following anterior cruciate ligament reconstruction - A case report.Trauma case reports · 2022Article
- Complex regional pain syndrome of the knee after conventional radiofrequency ablation of the genicular nerves treated successfully with dorsal root ganglion stimulation: A case report.Pain practice : the official journal of World Institute of Pain · 2022Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Knee osteoarthritis (KOA) is a common degenerative disease associated with joint dysfunction and pain. Ultrasound-guided radiofrequency (RF) may be a promising therapy in the treatment of chronic pain for KOA patients. Objective: To evaluate the efficacy and safety of ultrasound-guided RF treatment for chronic pain in patients with KOA. Design: A systematic review was conducted, and a meta-analysis was carried out when possible. Method: A systematic review for the efficacy and safety of ultrasound-guided RF treatment for pain management of KOA patients was carried out in PubMed, EMBASE, Cochrane Library, Web of Science, Wanfang Data, and China National Knowledge Infrastructure (CNKI) from the date of inception to February 2020, and a meta-analysis was conducted. The primary outcomes of pain intensity (visual analogue scale or numerical rating scale) and knee function [the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)] were evaluated from baseline to various follow-up times by random-effects model. Heterogeneity was assessed by Results: Eight publications with 256 patients were included in the meta-analysis. RF could relieve pain with -4.196 of pooled mean difference and improve knee function by decreasing 23.155 points in WOMAC. Three patients had ecchymosis, two with hypoesthesia and one with numbness after the procedure, and improved within 6 months. Furthermore, study design and treatment target were the sources of heterogeneity by subgroup and metaregression analyses, accounting for 37% and 74% of variances, respectively. Target of genicular nerve achieved better pain relief than intra-articular or sciatic nerve. Sensitivity analysis showed that removal of any single study was unlikely to overturn the findings. Conclusions: Ultrasonography is an effective, safe, nonradiative, and easily applicable guidance method for RF in pain relief and functional improvement in KOA patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.