Evidence map›Paper›PMID 33014189›Full record

ArticleDisease markers2020

Diagnostic and Prognostic Potentials of Long Noncoding RNA ELF3-AS1 in Glioma Patients.

Jun-Chi Mei, Ge Yan, Si-Qing Mei

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Disease markers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jun-Chi MeiDepartment of Laboratory Medicine, The Renmin Hospital of Wuhan University, Wuhan, 410060 Hubei Province, China.
Ge YanDepartment of Laboratory Medicine, The Maternal and Child Hospital of Hubei Province, Tongji Medical College, The Huazhong University of Science and Technology, Wuhan, 410060 Hubei Province, China.
Si-Qing MeiDepartment of Laboratory Medicine, The Renmin Hospital of Wuhan University, Wuhan, 410060 Hubei Province, China.ORCID https://orcid.org/0000-0003-4452-4327
Wuhan University · CNHuazhong University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAccumulating evidence implies that long noncoding RNAs (lncRNAs) play a crucial role in predicting survival for glioma patients. However, the potential function of lncRNA ELF3-antisense RNA 1 (ELF3-AS1) in tumors remained largely unclear. The aim of this study was to explore the expression of lncRNA ELF3-antisense RNA 1 (ELF3-AS1) and evaluate its functions in glioma patients.

resultsThe ELF3-AS1 expression level was significantly higher in glioma specimens compared with adjacent nontumor specimens (

conclusionsOur findings confirmed that ELF3-AS1 functions as an oncogene in glioma and indicated that ELF3-AS1 is not only an important prognostic marker but also a potential therapy target for glioma.

Indexed as

Biomarkers, TumorCell MovementCell ProliferationDNA-Binding ProteinsFemaleFollow-Up StudiesGene Expression Regulation, NeoplasticGliomaHumansMaleMiddle AgedPrognosisProto-Oncogene Proteins c-etsRNA, AntisenseRNA, Long NoncodingSurvival RateBiomarkers, TumorDNA-Binding ProteinsELF3 protein, humanProto-Oncogene Proteins c-etsRNA, AntisenseRNA, Long NoncodingTranscription Factors

Identifiers

PMID33014189
PMCPMC7519982
OpenAlexW3087168515

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.