Evidence map›Paper›PMID 33014137›Full record

ArticlePatient safety in surgery2020

Contributing factors to severe complications after liver resection: an aggregate root cause analysis in 105 consecutive patients.

Kholoud Houssaini, Oumayma Lahnaoui, Amine Souadka, Mohamed-Anass Majbar, Abdelilah Ghanam, Brahim El Ahmadi, Zakaria Belkhadir, Leila Amrani, Raouf Mohsine, Amine Benkabbou

Erratum issued Registry-linked trialAbstract read
In one paragraph

Article in Patient safety in surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT05286411 (Evaluation of the Implementation of a Quality Improvement Program Through Morbidity and Mortality Reviews in a Developing Country), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05286411 completednot on this map

Evaluation of the Implementation of a Quality Improvement Program Through Morbidity and Mortality Reviews in a Developing Country

TypeobservationalSponsorMoroccan Society of SurgeryRan2019 to 2020Enrolled13ConditionsQuality Improvement
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Kholoud HoussainiSurgical Oncology Department, National Institute of Oncology, Mohammed V University in Rabat, Rabat, Morocco.ORCID 0000-0002-3454-1281
Oumayma LahnaouiSurgical Oncology Department, National Institute of Oncology, Mohammed V University in Rabat, Rabat, Morocco.
Amine SouadkaSurgical Oncology Department, National Institute of Oncology, Mohammed V University in Rabat, Rabat, Morocco.
Mohamed-Anass MajbarSurgical Oncology Department, National Institute of Oncology, Mohammed V University in Rabat, Rabat, Morocco.
Abdelilah GhanamIntensive Care Department, National Institute of Oncology, Mohammed V University in Rabat, Rabat, Morocco.
Brahim El AhmadiIntensive Care Department, National Institute of Oncology, Mohammed V University in Rabat, Rabat, Morocco.
Zakaria BelkhadirIntensive Care Department, National Institute of Oncology, Mohammed V University in Rabat, Rabat, Morocco.
Leila AmraniSurgical Oncology Department, National Institute of Oncology, Mohammed V University in Rabat, Rabat, Morocco.
Raouf MohsineSurgical Oncology Department, National Institute of Oncology, Mohammed V University in Rabat, Rabat, Morocco.
Amine BenkabbouSurgical Oncology Department, National Institute of Oncology, Mohammed V University in Rabat, Rabat, Morocco.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aggregate root cause analysis (AggRCA) was designed to improve the understanding of system vulnerabilities contributing to patient harm, including surgical complications. It remains poorly used due to methodological complexity and resource limitations. This study aimed to identify the main patterns contributing to severe complications after liver resection using an AggRCA.

methodsThis was a retrospective qualitative study aimed to identify the main patterns contributing to severe complications, defined as strictly higher than grade IIIa according to the Clavien-Dindo classification within the first 90 days after liver resection. All consecutive severe complications that occurred between January 1st, 2018 and December 31st, 2019 were identified from an electronic database and included in an AggRCA. This included a structured morbidity and mortality review (MMR) reporting tool based on 50 contributory factors adapted from 6 ALARM categories: "Patient", "Tasks", "Individual staff", "Team", "Work environment", and "Management and Institutional context". Data resulting from individual-participant root cause analysis (RCA) of single-cases were validated collectively then aggregated. The main patterns were suggested from the contributory factors reported in more than half of the cases.

resultsIn 105 consecutive liver resection cases, 15 patients (14.3%) developed severe postoperative complications, including 5 (4.8%) who died. AggRCA resulted in the identification of 36 contributory factors. Eight contributory factors were reported in more than half of the cases and were compiled in three entangled patterns: (1) Disrupted perioperative process, (2) Unplanned intraoperative change, (3) Ineffective communication.

conclusionA pragmatic aggregated RCA process improved our understanding of system vulnerabilities based on the analysis of a limited number of events and a reasonable resource intensity. The identification of patterns contributing to severe complications lay the rationale of future contextualized safety interventions beyond the scope of liver resections.

Indexed as

Aggregate root cause analysisLiver resectionPatient safetyPostoperative complications

Identifiers

PMID33014137
PMCPMC7526378

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.