Evidence map›Paper›PMID 33014093›Full record

ReviewKardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery2020

Association of uromodulin with acute kidney injury in patients undergoing cardiac surgery.

Dariusz Chojęta, Małgorzata M Kozioł, Sylwia Targońska, Iwona Smarz-Widelska

Open access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Dariusz ChojętaStudents Scientific Association at the Chair and Department of Medical Microbiology, Medical University of Lublin, Lublin, Poland.
Małgorzata M KoziołChair and Department of Medical Microbiology, Medical University of Lublin, Lublin, Poland.
Sylwia TargońskaDepartment of Cardiac Surgery, Medical University of Lublin, Lublin, Poland.
Iwona Smarz-WidelskaDepartment of Nephrology, Cardinal Stefan Wyszynski Provincial Hospital, Lublin, Poland.
Medical University of Lublin · PLCardinal Stefan Wyszyński University in Warsaw · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Uromodulin (Umod) is a protein produced exclusively in the kidneys, and it is the most abundant protein in human urine. Scientific studies show that it can be a valuable diagnostic tool in monitoring kidney function. Clinical applications of Umod are probably wider. One of them is the role of a biomarker in cardiac surgery-associated acute kidney injury (CSA-AKI). Data from scientific studies indicate that a lower level of Umod in urine prior to surgery is associated with a higher risk of developing CSA-AKI after the procedure. A higher serum Umod level is suspected to be a good prognostic factor in the context of renal healing. It seems that the current state of knowledge supports the protective role of Umod in the course of AKI. Large, multi-center clinical trials would allow for the consolidation of preliminary scientific data and a more accurate understanding of the role of Umod as a CSA-AKI biomarker.

Indexed as

cardiac surgery-associated acute kidney injurykidney diseaseTamm-Horsfall proteinuromodulin

Identifiers

PMID33014093
PMCPMC7526493
OpenAlexW3089406615

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.