ArticleInternational journal of endocrinology2020
Associations of Triglyceride-Glucose Index and Its Derivatives with Hyperuricemia Risk: A Cohort Study in Chinese General Population.
Article in International journal of endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- The Association Between the Triglyceride Glucose Index and Hyperuricemia: A Dose-Response Meta-Analysis.Nutrients · 2025Pooled it
- The joint associations of TyG index and hsCRP with hyperuricemia among Chinese adults: a cross-sectional study.Clinical rheumatology · 2026Article
- Triglyceride-glucose index association with kidney function in adults; a population-based study.BMC endocrine disorders · 2025Article
- Association Between TyG-BMI Index and Hyperuricemia in Adult Women.Endocrinology, diabetes & metabolism · 2025Article
- Identifying metabolic parameters as key indicators of hyperuricemia and ischemic stroke comorbidity via interpretable Clinlabomics models.Frontiers in endocrinology · 2025Article
- Research status of triglyceride glucose-body mass index (TyG-BMI index).Frontiers in cardiovascular medicine · 2025Review
- Nonlinear association between triglyceride-glucose index and risk of hyperuricemia in early-stage cardiovascular-kidney-metabolic syndrome: a cross-sectional study of United States population.Frontiers in cardiovascular medicine · 2025Article
- Triglyceride-glucose index and its additive interaction withAnnals of medicine · 2024Article
- Association of triglyceride glucose index and triglyceride glucose-body mass index with sudden cardiac arrest in the general population.Cardiovascular diabetology · 2024Article
- Nonlinear association of triglyceride-glucose index with hyperuricemia in US adults: a cross-sectional study.Lipids in health and disease · 2024Article
- Association of triglyceride glucose-body mass index and hemoglobin glycation index with heart failure prevalence in hypertensive populations: a study across different glucose metabolism status.Lipids in health and disease · 2024Article
- Associations of triglyceride-glucose index with hyperuricemia among Royal Thai Army personnel.BMC endocrine disorders · 2024Article
- [Relationship of triglyceride-glucose index and its derivatives with blood pressure abnormalities in adolescents: an analysis based on a restricted cubic spline model].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024Article
- Sex-Based Differences in the Associations Between Obesity- and Lipid-Related Indexes and Hyperuricemia Risk in Patients with Obesity.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Article
- Triglyceride Glucose Body Mass Index as 3 Year Prognostic Indicator for Major Adverse Cardiovascular and Cerebrovascular Events in Patients with Acute Myocardial Infarction After PCI: A Prospective Cohort Study.Clinical interventions in aging · 2024Article
- Article
- Relationship between Atherogenic Dyslipidaemia and Lipid Triad and Scales That Assess Insulin Resistance.Nutrients · 2023Article
- Association between triglyceride glucose-body mass index and cardiovascular outcomes in patients undergoing percutaneous coronary intervention: a retrospective study.Cardiovascular diabetology · 2023Article
- Waist Circumference Is an Essential Factor in Predicting Insulin Resistance and Early Detection of Metabolic Syndrome in Adults.Nutrients · 2023Article
- Triglyceride-glucose index is significantly associated with the risk of hyperuricemia in patients with diabetic kidney disease.Scientific reports · 2022Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIdentification and intervention of insulin resistance may be beneficial to the prevention of hyperuricemia (HUA) and its related diseases. Thus, we conducted this longitudinal study to examine the relation of triglyceride-glucose index (TyG), a simple noninsulin-based IR assessment tool, and its derivatives with the risk of HUA.
methodsA total of 42,387 adults who received routine health screening and were free of HUA were included for the longitudinal analyses. TyG, body mass index (BMI), waist circumference (WC), and waist-to-height ratio (WtHR) were calculated through anthropometric and biochemical indicators. Associations of TyG, TyG-BMI, TyG-WC, and TyG-WHtR with HUA risk were estimated using Cox regression analyses.
resultsThe incident cases of HUA occurred in 4,230 subjects during the 138,163 person-years of observation, and the crude incidence rate of HUA was 30.6 per 1000 person-years. After multivariate adjustment, we observed an increased risk for incident HUA for the upper TyG and its derivatives' tercile. The HRs of TyG were greater than that of its components in both sexes. Compared with TyG, TyG-related parameters only had higher HRs in women but not in men.
conclusionsTyG and its integration with obesity indicators have the potential to help risk stratification and prevention of HUA, especially among women.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.