ArticleFrontiers in immunology2020
NK and T Cell Differentiation at the Maternal-Fetal Interface in Sows During Late Gestation.
Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Investigating the functional capacity of porcine uterine natural killer cells during a porcine reproductive and respiratory syndrome virus infection of pregnant gilts.Veterinary research · 2025Article
- The Complex Role of CD8+ T Cells in Placental HIV Infection.European journal of immunology · 2025Review
- Quantitative and longitudinal assessment of human placental inflammation using diffusion basis spectrum imaging.npj women's health · 2025Article
- Changes in Immune Response during Pig Gestation with a Focus on Cytokines.Veterinary sciences · 2024Review
- Porcine γδ T cells express cytotoxic cell-associated markers and display killing activity but are not selectively cytotoxic against PRRSV- or swIAV-infected macrophages.Frontiers in immunology · 2024Article
- Crosstalk between trace elements and T-cell immunity during early-life health in pigs.Science China. Life sciences · 2023Review
- Immunological uterine response to pig embryos before and during implantation.Reproduction in domestic animals = Zuchthygiene · 2022Review
- Role of hormones in the pregnancy and sex-specific outcomes to infections with respiratory viruses.Immunological reviews · 2022Review
- The immunobiology of preterm labor and birth: intra-amniotic inflammation or breakdown of maternal-fetal homeostasis.Reproduction (Cambridge, England) · 2022Review
- Influence of PRRSV-1 vaccination and infection on mononuclear immune cells at the maternal-fetal interface.Frontiers in immunology · 2022Article
- Revisiting the Transcriptome Landscape of Pig Embryo Implantation Site at Single-Cell Resolution.Frontiers in cell and developmental biology · 2022Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The phenotype and function of immune cells that reside at the maternal-fetal interface in humans and mice have been, and still are, extensively studied with the aim to fully comprehend the complex immunology of pregnancy. In pigs, information regarding immune cell phenotypes is limited and mainly focused on early gestation whereas late gestation has not yet been investigated. We designed a unique methodology tailored to the porcine epitheliochorial placenta, which allowed us to address immune phenotypes separately in the maternal endometrium (ME) and fetal placenta (FP) by flow cytometry. In-depth phenotyping of NK cells, non-conventional and conventional T cells within maternal blood (mBld), ME, FP, and fetal spleen (fSpln) revealed major differences between these anatomic sites. In both maternal compartments, all NK cells were perforin
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.