Evidence map›Paper›PMID 33013921›Full record

ArticleFrontiers in immunology2020

Human Cytomegalovirus-Induced Interleukin-10 Production Promotes the Proliferation of

Hailian Quan, Jiyeon Kim, Yi Rang Na, Jung Heon Kim, Byoung-Jun Kim, Bum-Joon Kim, Jung Joo Hong, Eung Soo Hwang, Seung Hyeok Seok

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. SubcutaneousJournal of veterinary science · 2023
    Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Hailian QuanDepartment of Microbiology and Immunology, Seoul National University College of Medicine, Seoul, South Korea.
Jiyeon KimDepartment of Microbiology and Immunology, Seoul National University College of Medicine, Seoul, South Korea.
Yi Rang NaDepartment of Microbiology and Immunology, Seoul National University College of Medicine, Seoul, South Korea.
Jung Heon KimInstitute of Endemic Disease, Seoul National University Medical Research Center, Seoul, South Korea.
Byoung-Jun KimDepartment of Microbiology and Immunology, Seoul National University College of Medicine, Seoul, South Korea.
Bum-Joon KimDepartment of Microbiology and Immunology, Seoul National University College of Medicine, Seoul, South Korea.
Jung Joo HongNational Primate Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, South Korea.
Eung Soo HwangDepartment of Microbiology and Immunology, Seoul National University College of Medicine, Seoul, South Korea.
Seung Hyeok SeokDepartment of Microbiology and Immunology, Seoul National University College of Medicine, Seoul, South Korea.
Seoul National University · KRSeoul National University Hospital · KRKorea Research Institute of Bioscience and Biotechnology · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human cytomegalovirus (HCMV) exploits the interleukin-10 (IL-10) pathway as a part of its infection cycle through the manipulation of the host IL-10 signaling cascade. Based on its immunomodulatory nature, HCMV attenuates the host immune response and facilitates the progression of co-infection with other pathogens in an immune-competent host. To investigate the impact of HCMV infection on the burden of non-tuberculous mycobacteria (NTM), whose prevalence is growing rapidly worldwide, macrophages were infected with HCMV and further challenged with

Indexed as

Cell ProliferationCoinfectionCytomegalovirus InfectionsMacrophagesMycobacterium Infections, NontuberculousCytomegalovirusHumansInterleukin-10Mycobacterium abscessusTHP-1 CellsIL10 protein, humanInterleukin-10human cytomegalovirusinterleukin-10macrophageMycobacterium massiliensenon-tuberculous mycobacteria

Identifiers

PMID33013921
PMCPMC7511582
OpenAlexW3084894641

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.