Evidence map›Paper›PMID 33013868›Full record

Trial reportFrontiers in immunology2020

Clinical Utility of Serial Measurements of Antineutrophil Cytoplasmic Antibodies Targeting Proteinase 3 in ANCA-Associated Vasculitis.

Gwen E Thompson, Lynn A Fussner, Amber M Hummel, Darrell R Schroeder, Francisco Silva, Melissa R Snyder, Carol A Langford, Peter A Merkel, Paul A Monach, Philip Seo and 4 more

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. New Biomarkers for Systemic Necrotizing Vasculitides.Journal of clinical medicine · 2024
    Review
  9. Article
  10. Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 10 institutions in 2 countries.

Gwen E ThompsonEssentia Health, Division of Pulmonary and Critical Care, Fargo, ND, United States.
Lynn A FussnerDivision of Pulmonary, Critical Care, and Sleep Medicine, The Ohio State University, Columbus, OH, United States.
Amber M HummelMayo Clinic and Mayo Foundation for Research and Education, Rochester, MN, United States.
Darrell R SchroederMayo Clinic and Mayo Foundation for Research and Education, Rochester, MN, United States.
Francisco SilvaDepartment of Rheumatology, Facultad de Medicina Clínica Alemana Universidad del Desarrollo, Santiago, Chile.
Melissa R SnyderMayo Clinic and Mayo Foundation for Research and Education, Rochester, MN, United States.
Carol A LangfordCleveland Clinic, Division of Rheumatology, Cleveland, OH, United States.
Peter A MerkelDivision of Rheumatology, Department of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Paul A MonachDivision of Rheumatology, Brigham and Women's Hospital, Boston, MA, United States.
Philip SeoDivision of Rheumatology, Johns Hopkins University, Baltimore, MD, United States.
Robert F SpieraDivision of Rheumatology, Hospital for Special Surgery, New York, NY, United States.
E William St ClairDivision of Rheumatology, Duke University, Durham, NC, United States.
John H StoneDivision of Rheumatology, Massachusetts General Hospital, Boston, MA, United States.
Ulrich SpecksMayo Clinic and Mayo Foundation for Research and Education, Rochester, MN, United States.
Mayo Clinic · USBrigham and Women's Hospital · USCleveland Clinic · USDuke University · USHospital for Special Surgery · USJohns Hopkins University · USMassachusetts General Hospital · USThe Ohio State University · USUniversidad del Desarrollo · CLUniversity of Pennsylvania · US

Funding

Immune Tolerance Network: Type 1 diabetesN01AI15416 · NIAID · UNIVERSITY OF SAN FRANCISCO · PI BLUESTONE, JEFFREY · 2007 to 2013
$276.6M
Institute for Clinical and Translational Research (UL1)UL1RR025005 · NCRR · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2007 to 2011
$75.8M
MAYO CLINIC CENTER FOR TRANSLATIONAL SCIENCE ACTIVITIESUL1RR024150 · NCRR · MAYO CLINIC ROCHESTER · PI RIZZA, ROBERT A. · 2006 to 2011
$66.4M
Mayo Clinic Center for Translational Science ActivitiesUL1TR000135 · NCATS · MAYO CLINIC ROCHESTER · PI KHOSLA, SUNDEEP · 2012 to 2015
$41.2M
YOGA INDUCED CHANGES IN BRAIN GABA LEVELSM01RR000533 · NCRR · BOSTON UNIVERSITY MEDICAL CAMPUS · PI HOLICK, MICHAEL F. · 1985 to 2008
$19.4M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025771 · NCRR · BOSTON UNIVERSITY MEDICAL CAMPUS · PI CENTER, DAVID M. · 2008 to 2011
$17.6M
Development of an ANCA-Vasculitis Index of Damage (AVID)K23AR052820 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI SEO, PHILIP · 2005 to 2009
$661k
Studies in Scleroderma and Cystic Fibrosis OsteoporosisK24AR002224 · NIAMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI MERKEL, PETER A · 2001 to 2005
$609k
Translational Research in Systemic VasculitisK24AR049185 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI STONE, JOHN H · 2003 to 2006
$351k
IMMUNE TOLERANCE NETWORK-266015416-266015416N01AI015416 · NIAID · REGENTS OF THE UNIVERSITY OF C · PI BLUESTONE, JEFFREY A · 2002 to 2006
–
NCATS NIH HHS UL1 TR000135NCRR NIH HHS M01 RR000533NCRR NIH HHS UL1 RR024150NCRR NIH HHS UL1 RR025005NCRR NIH HHS UL1 RR025771NIAID NIH HHS N01 AI015416NIAID NIH HHS N01AI15416NIAMS NIH HHS K23 AR052820NIAMS NIH HHS K24 AR002224NIAMS NIH HHS K24 AR049185
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antibodies, Antineutrophil CytoplasmicAnti-Neutrophil Cytoplasmic Antibody-Associated VasculitisBiomarkersCyclophosphamideHumansImmunoassayImmunosuppressive AgentsMyeloblastinRituximabSerologic TestsAntibodies, Antineutrophil CytoplasmicBiomarkersCyclophosphamideImmunosuppressive AgentsMyeloblastinRituximabANCA-associated vasculitisbiomarkerPR3-ANCArelapse activityremission

Identifiers

PMID33013868
PMCPMC7495134
OpenAlexW3083216752

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.