Evidence map›Paper›PMID 33013830›Full record

ArticleFrontiers in immunology2020

Monogenic Inflammatory Bowel Disease: It's Never Too Late to Make a Diagnosis.

Iddo Vardi, Irit Chermesh, Lael Werner, Ortal Barel, Tal Freund, Collin McCourt, Yael Fisher, Marina Pinsker, Elisheva Javasky, Batia Weiss and 6 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Red flags to suspect inborn errors of immunity in patients with autoimmune diseasesBiomedica : revista del Instituto Nacional de Salud · 2024
    Pooled it
  2. Review
  3. Monogenic inflammatory bowel disease: An unfolding enigma.World journal of clinical pediatrics · 2025
    Review
  4. Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 2 countries.

Iddo VardiPediatric Gastroenterology Unit, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Ramat Gan, Israel.
Irit ChermeshDepartment of Gastroenterology, Rambam Health Care Campus, Affiliated With Technion-Israel Institute of Technology, Haifa, Israel.
Lael WernerPediatric Gastroenterology Unit, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Ramat Gan, Israel.
Ortal BarelSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Tal FreundSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Collin McCourtDivision of Newborn Medicine, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, United States.
Yael FisherInstitute of Pathology, Rambam Health Care Campus, Affiliated With Technion-Israel Institute of Technology, Haifa, Israel.
Marina PinskerPediatric Gastroenterology Unit, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Ramat Gan, Israel.
Elisheva JavaskySackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Batia WeissPediatric Gastroenterology Unit, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Ramat Gan, Israel.
Gideon RechaviSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
David HaginSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Scott B SnapperDivision of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA, United States.
Raz SomechSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Liza KonnikovaDivision of Newborn Medicine, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, United States.
Dror S ShouvalPediatric Gastroenterology Unit, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Ramat Gan, Israel.
Tel Aviv University · ILChildren's Hospital of Pittsburgh · USEdmond and Lily Safra Children's Hospital · ILHarvard University · USRambam Health Care Campus · ILSheba Medical Center · ILTechnion – Israel Institute of Technology · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DNA Mutational AnalysisExome SequencingMutationAdaptor Proteins, Signal TransducingAdultCommon Variable ImmunodeficiencyDelayed DiagnosisGenetic Predisposition to DiseaseHumansInflammatory Bowel DiseasesMalePhenotypePredictive Value of TestsTime FactorsAdaptor Proteins, Signal TransducingLRBA protein, humancommon variable immunodeficiencyCTLA4enteropathyinflammatory bowel diseaseLRBAmonogenicwhole exome sequencing

Identifiers

PMID33013830
PMCPMC7509434
OpenAlexW3083190729

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.