Evidence map›Paper›PMID 33013734›Full record

ArticleFrontiers in microbiology2020

Expression Profile of Multidrug Resistance Efflux Pumps During Intracellular Life of Adherent-Invasive

Giulia Fanelli, Martina Pasqua, Bianca Colonna, Gianni Prosseda, Milena Grossi

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Giulia FanelliIstituto Pasteur Italia, Dipartimento di Biologia e Biotecnologie "Charles Darwin", Sapienza-Università di Roma, Rome, Italy.
Martina PasquaIstituto Pasteur Italia, Dipartimento di Biologia e Biotecnologie "Charles Darwin", Sapienza-Università di Roma, Rome, Italy.
Bianca ColonnaIstituto Pasteur Italia, Dipartimento di Biologia e Biotecnologie "Charles Darwin", Sapienza-Università di Roma, Rome, Italy.
Gianni ProssedaIstituto Pasteur Italia, Dipartimento di Biologia e Biotecnologie "Charles Darwin", Sapienza-Università di Roma, Rome, Italy.
Milena GrossiIstituto Pasteur Italia, Dipartimento di Biologia e Biotecnologie "Charles Darwin", Sapienza-Università di Roma, Rome, Italy.
Istituto Pasteur · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Efflux pumps (EPs) are present in all living cells and represent a large and important group of transmembrane proteins involved in transport processes. In bacteria, multidrug resistance efflux pumps (MDR EPs) confer resistance to antibiotics at different levels and are deeply implicated in the fast and dramatic emergence of antibiotic resistance. Recently, several reports have outlined the great versatility of MDR EPs in exporting a large variety of compounds other than antibiotics, thus promoting bacterial adaptation to a wide range of habitats. In several bacterial pathogens, MDR EPs contribute to increase the virulence potential and are directly involved in the crosstalk with host cells. In this work, we have investigated the possible role of MDR EPs in the infectious process of the adherent-invasive

Indexed as

adherent invasive Escherichia colibacteria-host interactionsbacterial transmembrane complexesefflux pumpsEscherichia coli pathogens

Identifiers

PMID33013734
PMCPMC7462009
OpenAlexW3077149899

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.