Evidence map›Paper›PMID 33013665›Full record

ReviewFrontiers in neurology2020

Astrocyte Glutamate Uptake and Signaling as Novel Targets for Antiepileptogenic Therapy.

Allison R Peterson, Devin K Binder

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.

  1. Pooled it
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  7. Article
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  12. TREK-1 and epilepsy: regulating the balance of KBehavioral and brain functions : BBF · 2025
    Review
  13. Article
  14. Review
  15. Empagliflozin Mitigates PTZ-Induced Seizures in Rats: Modulating Npas4 and CREB-BDNF Signaling Pathway.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2025
    Article
  16. Article
  17. Neuroglia and brain energy metabolism.Handbook of clinical neurology · 2025
    Review
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  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Allison R PetersonDivision of Biomedical Sciences, Center for Glial-Neuronal Interactions, School of Medicine, University of California, Riverside, Riverside, CA, United States.
Devin K BinderDivision of Biomedical Sciences, Center for Glial-Neuronal Interactions, School of Medicine, University of California, Riverside, Riverside, CA, United States.
University of California, Riverside · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Astrocytes regulate and respond to extracellular glutamate levels in the central nervous system (CNS)

Indexed as

astrocytesepilepsyGLASTGLT-1glutamate transportersmetabotropic glutamate receptorsmGluR3mGluR5

Identifiers

PMID33013665
PMCPMC7505989
OpenAlexW3084420951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.