Patient-Derived Midbrain Organoids to Explore the Molecular Basis of Parkinson's Disease.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

32 citing papers in PubMed.

1. Vascularized Brain Organoids: Advances in Engineering Human Neurovascular Models.International journal of stem cells · 2026
   Review
2. Organoids: From Bench to Bedside Applications.MedComm · 2026
   Review
3. Self-organized anteroposterior regionalization of early midbrain and hindbrain/spinal cords using micropatterned human pluripotent stem cells.SLAS technology · 2026
   Article
4. In vivo and in vitro perspectives in Parkinson's disease: Mechanisms and the role of phytomedicine.Journal of food and drug analysis · 2025
   Review
5. Advanced Animal Replacement Testing Strategies Using Stem Cell and Organoids.International journal of stem cells · 2025
   Review
6. Lewy pathology formation in patient-derived GBA1 Parkinson's disease midbrain organoids.Brain : a journal of neurology · 2025
   Article
7. Novel co-culture model of T cells and midbrain organoids for investigating neurodegeneration in Parkinson's disease.NPJ Parkinson's disease · 2025
   Article
8. Alpha synuclein and inflammaging.Heliyon · 2025
   Review
9. Shaping the Neurovascular Unit Exploiting Human Brain Organoids.Molecular neurobiology · 2024
   Review
10. Landscape of human organoids: Ideal model in clinics and research.Innovation (Cambridge (Mass.)) · 2024
    Review
11. Experimental Models to Study Immune Dysfunction in the Pathogenesis of Parkinson's Disease.International journal of molecular sciences · 2024
    Review
12. Autophagy and neuroprotection in astrocytes exposed to 6-hydroxydopamine is negatively regulated by NQO2: relevance to Parkinson's disease.Scientific reports · 2023
    Article
13. Human 3D brain organoids: steering the demolecularization of brain and neurological diseases.Cell death discovery · 2023
    Review
14. Parkinson's Disease: Exploring Different Animal Model Systems.International journal of molecular sciences · 2023
    Review
15. Lewy Body-like Pathology and Loss of Dopaminergic Neurons in Midbrain Organoids Derived from Familial Parkinson's Disease Patient.Cells · 2023
    Article
16. Histone lysine methyltransferase-related neurodevelopmental disorders: current knowledge and saRNA future therapies.Frontiers in cell and developmental biology · 2023
    Review
17. Midbrain organoids mimic early embryonic neurodevelopment and recapitulate LRRK2-p.Gly2019Ser-associated gene expression.American journal of human genetics · 2022
    Article
18. Multi-omic insights into Parkinson's Disease: From genetic associations to functional mechanisms.Neurobiology of disease · 2022
    Review
19. Research models of neurodevelopmental disorders: The right model in the right place.Frontiers in neuroscience · 2022
    Review
20. Human Brain-Based Models Provide a Powerful Tool for the Advancement of Parkinson's Disease Research and Therapeutic Development.Frontiers in neuroscience · 2022
    Review

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

3 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

Indexed as