Evidence map›Paper›PMID 33013632›Full record

ArticleFrontiers in neurology2020

Rapid Administration of High-Dose Intravenous Methylprednisolone Improves Visual Outcomes After Optic Neuritis in Patients With AQP4-IgG-Positive NMOSD.

Tetsuya Akaishi, Takayuki Takeshita, Noriko Himori, Toshiyuki Takahashi, Tatsuro Misu, Ryo Ogawa, Kimihiko Kaneko, Juichi Fujimori, Michiaki Abe, Tadashi Ishii and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 4 pooled it
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 4 syntheses or guidelines pooled it, 47 citations in OpenAlex.

  1. Guideline
  2. Guideline
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Changepoint analysis of longitudinal OCT in optic neuritis: Structural stabilization dynamics and clinical correlates.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  7. Article
  8. Review
  9. Relapse-related outcomes in the Danish population-based AQP4- antibody seropositive neuromyelitis optica spectrum disorder cohort.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Update on Optic Neuritis: An International View.Neuro-ophthalmology (Aeolus Press) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Tetsuya AkaishiDepartment of Neurology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Takayuki TakeshitaDepartment of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Noriko HimoriDepartment of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Toshiyuki TakahashiDepartment of Neurology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Tatsuro MisuDepartment of Neurology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Ryo OgawaDepartment of Neurology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Kimihiko KanekoDepartment of Neurology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Juichi FujimoriDepartment of Neurology, Tohoku Medical and Pharmaceutical University, Sendai, Japan.
Michiaki AbeDepartment of Education and Support for Regional Medicine, Tohoku University Hospital, Sendai, Japan.
Tadashi IshiiDepartment of Education and Support for Regional Medicine, Tohoku University Hospital, Sendai, Japan.
Kazuo FujiharaDepartment of Multiple Sclerosis Therapeutics, Fukushima Medical University, Fukushima, Japan.
Masashi AokiDepartment of Neurology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Toru NakazawaDepartment of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Ichiro NakashimaDepartment of Neurology, Tohoku Medical and Pharmaceutical University, Sendai, Japan.
Tohoku University · JPTohoku University Hospital · JPTohoku Medical and Pharmaceutical University · JPFukushima Medical University · JPNational Hospital Organization · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

neuromyelitis optica spectrum disordersoptic neuritissteroid pulse therapytimingvisual prognosis

Identifiers

PMID33013632
PMCPMC7505044
OpenAlexW3082756159

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.