Evidence map›Paper›PMID 33013434›Full record

ArticleFrontiers in physiology2020

Temporal Variability in Electrocardiographic Indices in Subjects With Brugada Patterns.

Sharen Lee, Jiandong Zhou, Tong Liu, Konstantinos P Letsas, Sandeep S Hothi, Vassilios S Vassiliou, Guoliang Li, Adrian Baranchuk, Raymond W Sy, Dong Chang and 2 more

Abstract read
In one paragraph

Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Risk stratification of sudden cardiac death in asymptomatic female Brugada syndrome patients: A literature review.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2023
    Review
  4. Article
  5. Article
  6. Observational
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sharen LeeLaboratory of Cardiovascular Physiology, Li Ka Shing Institute of Health Sciences, Hong Kong, China.
Jiandong ZhouSchool of Data Science, City University of Hong Kong, Hong Kong, China.
Tong LiuTianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin, China.
Konstantinos P LetsasSecond Department of Cardiology, Laboratory of Cardiac Electrophysiology, Evangelismos General Hospital of Athens, Athens, Greece.
Sandeep S HothiHeart and Lung Centre, New Cross Hospital, Wolverhampton, United Kingdom.
Vassilios S VassiliouNorwich Medical School, University of East Anglia, Faculty of Medicine, Imperial College London, London, United Kingdom.
Guoliang LiArrhythmia Unit, Department of Cardiovascular Medicine, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Adrian BaranchukDivision of Cardiology, Kingston General Hospital, Queen's University, Kingston, ON, Canada.
Raymond W SySydney Medical School, University of Sydney, Sydney, NSW, Australia.
Dong ChangXiamen Cardiovascular Hospital, Xiamen University, Xiamen, China.
Qingpeng ZhangSchool of Data Science, City University of Hong Kong, Hong Kong, China.
Gary TseTianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPatients with Brugada electrocardiographic (ECG) patterns have differing levels of arrhythmic risk. We hypothesized that temporal variations in certain ECG markers may provide additional value for risk stratification. The present study evaluated the relationship between temporal variability of ECG markers and arrhythmic outcomes in patients with a Brugada pattern ECG. Comparisons were made between low-risk asymptomatic subjects versus high-risk symptomatic patients with a history of syncope, ventricular tachycardia (VT) or ventricular fibrillation (VF).

methodsA total of 81 patients presenting with Brugada patterns were recruited. Serial ECGs and electronic health records from January 2004 to April 2019 were analyzed. Temporal variability of QRS interval, J point-T

resultsPatients presenting with type 1 Brugada ECG pattern initially had significantly higher variability in JTp from lead V2 (SD: 33.5 ± 13.8 vs. 25.2 ± 11.5 ms,

conclusionTemporal variability in ECG indices may provide additional value for risk stratification in patients with Brugada pattern.

Indexed as

BrugadaECGrepolarizationtemporalvariability

Identifiers

PMID33013434
PMCPMC7494959

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.