Evidence map›Paper›PMID 33013378›Full record

ArticleFrontiers in pharmacology2020

Recombinant Ricin Toxin Binding Subunit B (RTB) Stimulates Production of TNF-α by Mouse Macrophages Through Activation of TLR4 Signaling Pathway.

Na Xu, Kaikai Yu, Haotian Yu, Jianxu Zhang, Yang Yang, Mingxin Dong, Yan Wang, Ying Chang, Yucheng Sun, Yanguang Hou and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Toll like receptor 4 (TLR4) in neuroinflammation: From acute hemorrhagic stroke to chronic neurodegeneration.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Review
  2. Advanced pharmaceutical bulletin · 2024
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Na XuInstitute of Military Veterinary Medicine, Academy of Military Medical Sciences, Zoonosis Prevention and Control Key Laboratory, Changchun, China.
Kaikai YuInstitute of Military Veterinary Medicine, Academy of Military Medical Sciences, Zoonosis Prevention and Control Key Laboratory, Changchun, China.
Haotian YuInstitute of Military Veterinary Medicine, Academy of Military Medical Sciences, Zoonosis Prevention and Control Key Laboratory, Changchun, China.
Jianxu ZhangInstitute of Military Veterinary Medicine, Academy of Military Medical Sciences, Zoonosis Prevention and Control Key Laboratory, Changchun, China.
Yang YangInstitute of Translational Medicine, First Hospital of Jilin University, Changchun, China.
Mingxin DongInstitute of Military Veterinary Medicine, Academy of Military Medical Sciences, Zoonosis Prevention and Control Key Laboratory, Changchun, China.
Yan WangInstitute of Military Veterinary Medicine, Academy of Military Medical Sciences, Zoonosis Prevention and Control Key Laboratory, Changchun, China.
Ying ChangInstitute of Military Veterinary Medicine, Academy of Military Medical Sciences, Zoonosis Prevention and Control Key Laboratory, Changchun, China.
Yucheng SunInstitute of Military Veterinary Medicine, Academy of Military Medical Sciences, Zoonosis Prevention and Control Key Laboratory, Changchun, China.
Yanguang HouInstitute of Military Veterinary Medicine, Academy of Military Medical Sciences, Zoonosis Prevention and Control Key Laboratory, Changchun, China.
Chengbiao SunInstitute of Military Veterinary Medicine, Academy of Military Medical Sciences, Zoonosis Prevention and Control Key Laboratory, Changchun, China.
Jiayu WanInstitute of Military Veterinary Medicine, Academy of Military Medical Sciences, Zoonosis Prevention and Control Key Laboratory, Changchun, China.
Wensen LiuInstitute of Military Veterinary Medicine, Academy of Military Medical Sciences, Zoonosis Prevention and Control Key Laboratory, Changchun, China.
Academy of Military Medical Sciences · CNFirst Hospital of Jilin University · CNJilin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ricin toxin binding subunit B (RTB) is a galactose-binding lectin protein derived from the beans of the castor oil plant (

Indexed as

cytokinemacrophagericin toxin binding subunit Bsignaling pathwayTLR4

Identifiers

PMID33013378
PMCPMC7506049
OpenAlexW3084203911

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.