Evidence map›Paper›PMID 33013250›Full record

ArticleDose-response : a publication of International Hormesis Society

Study on the Fingerprints and Quality Evaluation of Angelica Sinensis Radix by HPLC Coupled With Chemometrics Based on Traditional Decoction Process of ACPTCM.

Zhang Qian, Chen Yiyang, Ma Lixia, Jiang Yue, Chen Jun, Dong Jie, Ma Yifan, Zhang Jingjing, Yan Guojun

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Article in Dose-response : a publication of International Hormesis Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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5citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Comparative study onFood chemistry: X · 2023
    Article
  4. Antibacterial mechanism of areca nut essential oils againstFrontiers in cellular and infection microbiology · 2023
    Article
  5. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhang QianSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.ORCID https://orcid.org/0000-0002-8201-4603
Chen YiyangSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Ma LixiaSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Jiang YueSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Chen JunSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Dong JieSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Ma YifanDepartment of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH, USA.
Zhang JingjingDepartment of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH, USA.
Yan GuojunSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.ORCID https://orcid.org/0000-0002-6686-0906

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo establish a HPLC fingerprints evaluation method for

methodsThe fingerprints of 10 batches of ASR were further evaluated by chemometrics methods. The similarity analyzed with "Similarity Evaluation System for Chromatographic Fingerprint of Traditional Chinese Medicine 2004A," and hierarchical clustering analysis (HCA) and principal component analysis (PCA) were performed by SPSS (version 22.0, SPSS Inc., Chicago, IL, USA).

resultsThere were 12 common peaks, and the similarity degrees of 10 batches of samples were more than 0.923 and showed that all the samples from different origins were of good consistency. The samples were divided into 4 clusters by HCA. The results of PCA showed that the 3 factors were chosen, the quality of samples could be evaluated basically. The comprehensive score results show that the ASR with Lot.Nos.DG-18007, DG-18008 in Weiyuan County, Gansu and DG-18009 produced in Minle County, Gansu Province rank among the top 3 in all samples.

conclusionsThese results demonstrated that the combination of HPLC chromatographic fingerprint and chemometrics offers an efficient and reliable approach for quality evaluation of ASR from different sources as Ancient Classical Prescriptions ingredients.

Indexed as

angelica sinensis radixchemometricsfingerprintHPLCquality evaluation

Identifiers

PMID33013250
PMCPMC7513407

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