Evidence map›Paper›PMID 33012972›Full record

ArticleCanadian journal of veterinary research = Revue canadienne de recherche veterinaire2020

Integrin alpha-v/beta3 expression in equine lungs and jejunum.

Nguyen Phuong Khanh Le, Volker Gerdts, Baljit Singh

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Nguyen Phuong Khanh LeWestern College of Veterinary Medicine (Le, Gerdts, Singh) and Vaccine and Infectious Disease Organization - International Vaccine Centre (Gerdts), University of Saskatchewan, Saskatoon, Saskatchewan S7N 5B4; Faculty of Animal Science and Veterinary Medicine, Nong Lam University, Ho Chi Minh City, Vietnam (Le); Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta T2N 4Z6 (Singh).
Volker GerdtsWestern College of Veterinary Medicine (Le, Gerdts, Singh) and Vaccine and Infectious Disease Organization - International Vaccine Centre (Gerdts), University of Saskatchewan, Saskatoon, Saskatchewan S7N 5B4; Faculty of Animal Science and Veterinary Medicine, Nong Lam University, Ho Chi Minh City, Vietnam (Le); Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta T2N 4Z6 (Singh).
Baljit SinghWestern College of Veterinary Medicine (Le, Gerdts, Singh) and Vaccine and Infectious Disease Organization - International Vaccine Centre (Gerdts), University of Saskatchewan, Saskatoon, Saskatchewan S7N 5B4; Faculty of Animal Science and Veterinary Medicine, Nong Lam University, Ho Chi Minh City, Vietnam (Le); Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta T2N 4Z6 (Singh).
University of Saskatchewan · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Integrin alpha-v/beta3 (αvβ3) recognizes arginine-glycine-aspartic acid (RGD) sequences and has important functions in cell adhesion, signaling, and survival. However, the expression of integrin αvβ3 in the equine lungs and jejunum is not well understood. The objective of this study was to explore the hitherto unknown expression of integrin αvβ3 in the lungs and jejuna of the horse using light and electron immunocytochemistry. Immunohistochemistry showed integrin αvβ3 on the epithelium, the immune cells in Peyer's patches, the smooth muscle, and the endothelium of equine jejuna. In equine lungs, we recognized integrin αvβ3 on the endothelium of blood vessels, the alveolar septa, the bronchial lymph nodes, and the cartilages, although the expression of integrin αvβ3 was weak on the epithelium of bronchioles. In conclusion, these are the first data to show the expression of integrin αvβ3 in equine lungs and jejuna.

Indexed as

AnimalsGene Expression RegulationHorsesIntegrin alphaVbeta3JejunumLungIntegrin alphaVbeta3

Identifiers

PMID33012972
PMCPMC7491005
OpenAlexW3090543534

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.