Evidence map›Paper›PMID 33011554›Full record

ArticleJournal of anxiety disorders2020

Family accommodation mediates the impact of childhood anxiety on functional impairment.

Pedro Macul Ferreira de Barros, Natália Polga, Natalia Szejko, Eurípedes Constantino Miguel, James Frederick Leckman, Wendy K Silverman, Eli R Lebowitz

Open access · greenAbstract read
In one paragraph

Article in Journal of anxiety disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Peer and familial influences on the association between behavioral inhibition and trajectories of social anxiety symptoms across adolescence.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2026
    Article
  3. Transdiagnostic correlates of family accommodation in anxious youth.Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43) · 2025
    Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Pedro Macul Ferreira de BarrosInstitute of Psychiatry, University of São Paulo, São Paulo, Brazil. Electronic address: pedro.macul@hc.fm.usp.br.
Natália PolgaInstitute of Psychiatry, University of São Paulo, São Paulo, Brazil.
Natalia SzejkoDepartment of Neurology, Medical University of Warsaw, Warsaw, Poland.
Eurípedes Constantino MiguelInstitute of Psychiatry, University of São Paulo, São Paulo, Brazil.
James Frederick LeckmanYale Child Study Center, Yale University School of Medicine, New Haven, USA.
Wendy K SilvermanYale Child Study Center, Yale University School of Medicine, New Haven, USA.
Eli R LebowitzYale Child Study Center, Yale University School of Medicine, New Haven, USA.
Universidade de São Paulo · BRYale University · USMedical University of Warsaw · PL

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Brain response associated with parent-based treatment for childhood anxiety disordersR61MH115113 · NIMH · YALE UNIVERSITY · PI GEE, DYLAN GRACE, LEBOWITZ, ELI · 2018 to 2019
$1.5M
Explanatory Clinical Trial of a Novel Parent Intervention for Childhood AnxietyK23MH103555 · NIMH · YALE UNIVERSITY · PI LEBOWITZ, ELI · 2014 to 2017
$703k
NCATS NIH HHS UL1 TR001863NIMH NIH HHS K23 MH103555NIMH NIH HHS R61 MH115113
6 · The paper itself

Abstract

backgroundAnxiety disorders are the most common childhood-onset psychiatric disorders and are extensively associated with child functional impairment. Data suggest that family accommodation plays a role in the association between anxiety severity and functional impairment in children, but more empirical evidence is needed.

methodsParticipants were 425 clinically anxious children (ages 6-17 years), and their mothers. We first examined associations between child anxiety symptom severity, family accommodation, and child functional impairment. Next, we investigated the hypothesized mediation pathway linking anxiety severity to child impairment through increased family accommodation using structural equation modeling. We tested two models: one using parent ratings of their child's anxiety and the other using the child's self-ratings. Finally, we estimated the effect sizes of the mediation pathway in both models.

resultsFamily accommodation was significantly correlated with all the study variables. Child functional impairment was significantly correlated with parent-rated and self-rated child anxiety severity. Both structural equation models provided excellent fit for the data and supported the theoretical model by which family accommodation significantly explains part of the association between anxiety symptoms and functional impairment. The indirect effect sizes indicate that family accommodation accounts for between a fifth and a half of the impairment associated with symptom severity.

conclusionsThe data provide important empirical evidence that family accommodation mediates the association between child anxiety and functional impairment and accounts for up to 50 % of this association. These findings contribute to the growing understanding of the critical role of family accommodation and underscore the importance of assessing accommodation when evaluating and treating anxious children.

Indexed as

Anxiety DisordersChild Behavior DisordersAdolescentAnxietyChildFemaleHumansMothersParentsAnxietyChild and adolescentFamily accommodationMediation analysisParenting

Identifiers

PMID33011554
PMCPMC7680363
OpenAlexW3090808934

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.