Evidence map›Paper›PMID 33011454›Full record

ReviewCurrent opinion in biotechnology2020

Genome editing systems across yeast species.

Zhiliang Yang, Mark Blenner

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Biological Upcycling of Plastics Waste.Annual review of chemical and biomolecular engineering · 2024
    Review
  9. Article
  10. Article
  11. Editorial: Genomic strategies for efficient microbial cell factories.Frontiers in bioengineering and biotechnology · 2022
    Article
  12. Tips, Tricks, and Potential Pitfalls of CRISPR Genome Editing inFrontiers in bioengineering and biotechnology · 2022
    Review
  13. Review
  14. Evaluation ofMicroorganisms · 2021
    Article
  15. Review
  16. Review
  17. The Model SystemLife (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Zhiliang YangDepartment of Chemical & Biomolecular Engineering, Clemson University, Clemson, SC 29634, United States.
Mark BlennerDepartment of Chemical & Biomolecular Engineering, Clemson University, Clemson, SC 29634, United States. Electronic address: blenner@clemson.edu.
Clemson University · US

Funding

Enabling Plant Natural Product Biosynthesis by Debugging Heterologous Protein Expression in YeastR35GM133803 · NIGMS · UNIVERSITY OF DELAWARE · PI BLENNER, MARK ALAN · 2019 to 2023
$2.0M
NIGMS NIH HHS R35 GM133803
6 · The paper itself

Abstract

Yeasts are used to produce a myriad of value-added compounds. Engineering yeasts into cost-efficient cell factories is greatly facilitated by the availability of genome editing tools. While traditional engineering techniques such as homologous recombination-based gene knockout and pathway integration continue to be widely used, novel genome editing systems including multiplexed approaches, bacteriophage integrases, CRISPR-Cas systems, and base editors are emerging as more powerful toolsets to accomplish rapid genome scale engineering and phenotype screening. In this review, we summarized the techniques which have been successfully implemented in model yeast Saccharomyces cerevisiae as well as non-conventional yeast species. The mechanisms and applications of various genome engineering systems are discussed and general guidelines to expand genome editing systems from S. cerevisiae to other yeast species are also highlighted.

Indexed as

BacteriophagesGene EditingCRISPR-Cas SystemsPhylogenySaccharomyces cerevisiae

Identifiers

PMID33011454
PMCPMC7744358
OpenAlexW3091052652

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.