ArticleJACC. Cardiovascular interventions2020
Electrosurgical Detachment of MitraClips From the Anterior Mitral Leaflet Prior to Transcatheter Mitral Valve Implantation.
Article in JACC. Cardiovascular interventions, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
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Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- Mitral Valve Leaflet Modification: A Working Group Position Statement on Best Practices and Step-by-Step Guide.JACC. Cardiovascular interventions · 2026Guideline
- Transcatheter management of residual mitral regurgitation after transcatheter edge-to-edge repair: a systematic review.Cardiovascular intervention and therapeutics · 2025Pooled it
- Review
- Percutaneous Treatment of Mitral Regurgitation After Failed Mitral Transcatheter Edge-to-Edge Repair.Journal of cardiovascular development and disease · 2025Review
- Transcatheter mitral valve replacement or repair for mitral regurgitation: a narrative review.Indian journal of thoracic and cardiovascular surgery · 2025Review
- Electrosurgical Laceration and Stabilization of a Failed Mitral Edge-to-Edge Device Before Transcatheter Mitral Valve Replacement: The Importance of a Trans-Septal Approach.JACC. Case reports · 2025Article
- Clip Liberation to Facilitate Transcatheter Tricuspid Valve Replacement (CLEFT).JACC. Case reports · 2025Article
- Wire-Based Interventional Clip Excision (WICE Procedure) to Allow Transcatheter Tricuspid Valve Replacement.JACC. Case reports · 2025Article
- Electrosurgical-laceration and stabilization of two PASCAL devices using artificial intelligence-based procedural planning: a case report.European heart journal. Case reports · 2025Article
- Expanding the Clinical Horizon of Transcatheter Interventions: Addressing the Complications of Endocarditis.JACC. Case reports · 2025Article
- Transcatheter mitral valve implantation using TENDYNE valve for the treatment of residual severe mitral regurgitation post-transcatheter mitral valve edge-to-edge repair: a case report.European heart journal. Case reports · 2024Article
- Devices and approaches for leaflet modification.JTCVS structural and endovascular · 2024Article
- Simplified ELASTA-CLIP Before Transapical Mitral Valve Replacement.JACC. Case reports · 2023Article
- Transapical electrosurgical laceration and stabilization of mitral clips followed by transcatheter mitral valve replacement-A one-stop shop.JTCVS techniques · 2023Article
- Repeat Mitral Transcatheter Edge-to-Edge Repair for Recurrent Significant Mitral Regurgitation.Journal of the American Heart Association · 2023Article
- Transcatheter Electrosurgery: A Narrative Review.Circulation. Cardiovascular interventions · 2023Review
- Chordal Preservation Mitral Valve Replacement for Delayed MitraClip Failure.Texas Heart Institute journal · 2022Article
- Recurrent or Persistent Mitral Regurgitation After Transcatheter Edge-to-Edge Repair: It Is a Big Deal!Journal of the American Heart Association · 2022Article
- Mitral Valve Surgery for Persistent or Recurrent Mitral Regurgitation After Transcatheter Edge-to-Edge Repair Is Associated With Improved Survival.Journal of the American Heart Association · 2022Article
- Complications of the Percutaneous Mitral Valve Edge-To-Edge Repair: Role of Transesophageal Echocardiography.Journal of clinical medicine · 2022Review
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17 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesThe aim of this study was to test the hypothesis that transcatheter electrosurgery might allow intentional detachment of previously placed MitraClip(s) from the anterior leaflet to recreate a single mitral orifice for transcatheter mitral valve implantation (TMVI), leaving the retained MitraClip(s) securely fastened to the posterior leaflet and without interfering with the mitral bioprosthesis.
backgroundPatients with severe mitral regurgitation or stenosis despite edge-to-edge mitral repair with the MitraClip typically have few therapeutic options because the resultant double orifice precludes TMVI. Transcatheter electrosurgery may allow detachment of failed MitraClip(s) from the anterior leaflet to recreate a single orifice for TMVI.
methodsThis was a single-center, 5-patient, consecutive, retrospective observational cohort. Patients underwent transcatheter electrosurgical laceration and stabilization of failed MitraClip(s) to recreate a single orifice, leaving the MitraClip(s) securely fastened to the posterior leaflet. Subsequently, patients underwent TMVI with an investigational device, the Tendyne mitral bioprosthesis, on a compassionate basis. Patients were followed up to 30 days.
resultsMitraClip detachment from the anterior leaflet and Tendyne implantation were successful in all patients. All patients survived to discharge. All patients were discharged with grade 0 central mitral regurgitation. Two patients had moderate perivalvular mitral regurgitation that did not require reintervention. During the follow-up period of 30 days, there were no deaths, cases of valve dysfunction, or reintervention. There was no evidence of erosion or bioprosthetic valve dysfunction attributable to the retained MitraClip(s) still attached to the posterior leaflet.
conclusionsTranscatheter electrosurgical detachment of failed MitraClips from the anterior leaflet followed by TMVI is technically feasible and safe at 30 days. Longer term study is needed to determine the clinical benefit of this approach and new algorithms for TMVI sizing following electrosurgical laceration and stabilization of a failed MitraClip to avoid perivalvular leak.
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