Evidence map›Paper›PMID 33010801›Full record

ArticleBMC pediatrics2020

Extended spectrum beta-lactamase and fluoroquinolone resistance genes among Escherichia coli and Salmonella isolates from children with diarrhea, Burkina Faso.

René Dembélé, Ali Konaté, Oumar Traoré, Wendpoulomdé A D Kaboré, Issiaka Soulama, Assèta Kagambèga, Alfred S Traoré, Nathalie K Guessennd, Awa Aidara-Kane, Amy Gassama-Sow and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
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  10. Molecular Epidemiology ofMicroorganisms · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

René DembéléLaboratory of Molecular Biology, Epidemiology and Surveillance of Bacteria and Viruses Transmitted by Food, Centre for Research in Biological, Food and Nutritional Sciences, Graduate School of Science and Technology, University Joseph KI-ZERBO, 03, BP 7021, Ouagadougou 03, Burkina Faso. simavedemb@gmail.com.ORCID 0000-0002-9282-8555
Ali KonatéLaboratory of Molecular Biology, Epidemiology and Surveillance of Bacteria and Viruses Transmitted by Food, Centre for Research in Biological, Food and Nutritional Sciences, Graduate School of Science and Technology, University Joseph KI-ZERBO, 03, BP 7021, Ouagadougou 03, Burkina Faso.
Oumar TraoréLaboratory of Molecular Biology, Epidemiology and Surveillance of Bacteria and Viruses Transmitted by Food, Centre for Research in Biological, Food and Nutritional Sciences, Graduate School of Science and Technology, University Joseph KI-ZERBO, 03, BP 7021, Ouagadougou 03, Burkina Faso.
Wendpoulomdé A D KaboréLaboratory of Molecular Biology, Epidemiology and Surveillance of Bacteria and Viruses Transmitted by Food, Centre for Research in Biological, Food and Nutritional Sciences, Graduate School of Science and Technology, University Joseph KI-ZERBO, 03, BP 7021, Ouagadougou 03, Burkina Faso.
Issiaka SoulamaNational Centre for Research and Training on Malaria, 01, BP 2208, Ouagadougou 01, Burkina Faso.
Assèta KagambègaLaboratory of Molecular Biology, Epidemiology and Surveillance of Bacteria and Viruses Transmitted by Food, Centre for Research in Biological, Food and Nutritional Sciences, Graduate School of Science and Technology, University Joseph KI-ZERBO, 03, BP 7021, Ouagadougou 03, Burkina Faso.
Alfred S TraoréLaboratory of Molecular Biology, Epidemiology and Surveillance of Bacteria and Viruses Transmitted by Food, Centre for Research in Biological, Food and Nutritional Sciences, Graduate School of Science and Technology, University Joseph KI-ZERBO, 03, BP 7021, Ouagadougou 03, Burkina Faso.
Nathalie K GuessenndLaboratory of Bacteriology-Virology, Unit of Antibiotics, Natural Substances and Surveillance of Resistance of Microorganisms to Antimicrobials, Pasteur Institute of Abidjan, 01, BP 490, Abidjan 01, Ivory Coast.
Awa Aidara-KaneUnit of Experimental Bacteriology, Pasteur Institute of Dakar, 36 Avenue Pasteur, BP 220, Dakar, Senegal.
Amy Gassama-SowUnit of Experimental Bacteriology, Pasteur Institute of Dakar, 36 Avenue Pasteur, BP 220, Dakar, Senegal.
Nicolas BarroLaboratory of Molecular Biology, Epidemiology and Surveillance of Bacteria and Viruses Transmitted by Food, Centre for Research in Biological, Food and Nutritional Sciences, Graduate School of Science and Technology, University Joseph KI-ZERBO, 03, BP 7021, Ouagadougou 03, Burkina Faso.
Université Joseph Ki-Zerbo · BFInstitut Pasteur de Dakar · SNInstitut Pasteur de Côte d'Ivoire · CIMalariaGEN · BF

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe emergence and spread of multidrug-resistant gram-negative bacteria (MDR) has become a major public health concern worldwide. This resistance is caused by enzymes-mediated genes (i.e., extended spectrum beta-lactamases) that are common in certain Enterobacterioceae species. However, the distribution of these genes is poorly documented in Burkina Faso. This study aims to determine the prevalence and distribution of the resistant genes coding for broad spectrum beta-lactamases and quinolones in rural Burkina Faso.

methodsMultiplex PCR assays were carried out to detect ESBL-encoding genes, including bla

resultsThe Extended-Spectrum Beta-Lactamases (ESBL) resistance phenotype was reported in all the E. coli isolates (5/5). Cross-resistance phenotype to quinolones (CRQ) was shown by one Salmonella strain (1/9) and three E. coli (3/5). Cross-resistance phenotypes to fluoroquinolones (CRFQ) were harboured by one Salmonella (1/9) and carbapenemase phenotypes were detected in two E. coli strains (2/5). Whilst the bla

conclusionsThis study identified β-lactam (bla) and quinolone resistance (qnr) genes in multidrug-resistant E. coli and Salmonella spp. in rural Burkina Faso. Our finding which highlighted the enterobacteriaceae strains resistance to β-lactams and quinolones are of high interest for adequate management of antimicrobial resistant genes outbreak in Burkina Faso.

Indexed as

Escherichia coliEscherichia coli InfectionsAnti-Bacterial Agentsbeta-LactamasesBurkina FasoChildDiarrheaFluoroquinolonesHumansMicrobial Sensitivity TestsSalmonellaAnti-Bacterial Agentsbeta-LactamasesFluoroquinolonesAntibioticsblaCTX−MblaOXAqnrBResistance genes

Identifiers

PMID33010801
PMCPMC7532561
OpenAlexW3090083575

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.