Evidence map›Paper›PMID 33010793›Full record

ArticlePediatric research2021

Respiratory, growth, and survival outcomes of infants with tracheostomy and ventilator dependence.

Gangaram Akangire, Jane B Taylor, Susan McAnany, Janelle Noel-MacDonnell, Charisse Lachica, Venkatesh Sampath, Winston Manimtim

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Pediatric research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Change over time in intensive care unit transition after pediatric tracheotomy: A 28-year analysis of shifting outcomes.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  4. Interdisciplinary clinical bronchopulmonary dysplasia programs: development, evolution, and maturation.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. The NICU tracheostomy team: multidisciplinary collaboration for improvement in survival of complex patients.Journal of perinatology : official journal of the California Perinatal Association · 2024
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Survival and decannulation across indications for infant tracheostomy: a twelve-year single-center cohort study.Journal of perinatology : official journal of the California Perinatal Association · 2022
    Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Gangaram AkangireDivision of Neonatology, Children's Mercy Kansas City, Kansas City, MO, USA. gakangire@cmh.edu.
Jane B TaylorDivision of Pulmonology, University of Pittsburgh Medical Center-Children's Hospital of Pittsburgh, Pittsburgh, PA, USA.
Susan McAnanyDivision of Neonatology, Children's Mercy Kansas City, Kansas City, MO, USA.
Janelle Noel-MacDonnellDepartment of Pediatrics, School of Medicine, University of Missouri Kansas City, Kansas City, MO, USA.
Charisse LachicaDivision of Neonatology, Children's Mercy Kansas City, Kansas City, MO, USA.
Venkatesh SampathDivision of Neonatology, Children's Mercy Kansas City, Kansas City, MO, USA.
Winston ManimtimDivision of Neonatology, Children's Mercy Kansas City, Kansas City, MO, USA.
Children's Mercy Hospital · USUniversity of Missouri–Kansas City · USChildren's Hospital of Pittsburgh · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOutcome of infants with tracheostomy have not been well described in the literature. Our objective was to describe the respiratory, growth, and survival outcomes of infants with tracheostomy.

methodsA retrospective study was conducted on 204 infants born between 2005 and 2015 with tracheostomy at <1 year of age and follow-up in the Infant Tracheostomy and Home Ventilator Clinic up to 4 years of age.

resultsThe mean age at tracheostomy was 4.5 months with median age of 3 months. Median age of decannulation was 32 months. The time from tracheostomy placement to complete discontinuation of mechanical ventilation was 15.4 months and from tracheostomy to decannulation was 33.8 months. Mortality rate was 21% and median age of death was 18 months. Preterm infants with acquired airway and lung disease (BPD) and born at <28 weeks' gestation had a significantly higher survival rate compared to term infants. The z-scores for weight and weight for length improved from the time of discharge (mean chronological age 6.5 months) to first year and remained consistent through 3 years.

conclusionsPremature infants had a higher rate of discontinuation of mechanical ventilation and decannulation compared to term infants. These infants showed consistent growth and comparable survival rate. IMPACT: Infants with tracheostomy and ventilator dependence followed in a multidisciplinary clinic model may have improved survival, growth, and earlier time to decannulation. Preterm infants with acquired airway and lung disease (BPD) with tracheostomy had a higher survival rate compared to term infants with various tracheostomy indications. The age at tracheostomy in infants was 4.5 months and of decannulation was 37 months. Time from tracheostomy to complete discontinuation of mechanical ventilation was 15.4 months. Addition of this data to the sparse literature will be crucial in counseling the families and education of medical staff.

Indexed as

Child DevelopmentRespiration, ArtificialTracheostomyAge FactorsChild, PreschoolFemaleGestational AgeHumansInfantInfant, Extremely PrematureLungLung DiseasesMaleRecovery of FunctionRetrospective StudiesRisk Assessment

Identifiers

PMID33010793
PMCPMC7605149
OpenAlexW3089755697

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.