Evidence map›Paper›PMID 33010408›Full record

ArticleClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2022

Program Components and Results From an Organized Colorectal Cancer Screening Program Using Annual Fecal Immunochemical Testing.

Kevin Selby, Christopher D Jensen, Theodore R Levin, Jeffrey K Lee, Joanne E Schottinger, Wei K Zhao, Douglas A Corley, Chyke A Doubeni

Abstract read
In one paragraph

Article in Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Quality indicators for colonoscopy.Gastrointestinal endoscopy · 2024
    Guideline
  2. Trial
  3. Trial
  4. Longitudinal Adherence With Stool-Based Testing for Colorectal Cancer Screening in Four United States Health Systems.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Review
  11. Article
  12. Quality Indicators for Colonoscopy.The American journal of gastroenterology · 2024
    Article
  13. Improving Colorectal Cancer Screening via Mailed Fecal Immunochemical Testing in a Veterans Affairs Health System.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Observational
  18. Unsatisfactory Fecal Immunochemical Tests for Colorectal Cancer Screening: Prevalence, Reasons, and Subsequent Testing.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kevin SelbyCenter for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland. Electronic address: kevin.selby@unisante.ch.
Christopher D JensenKaiser Permanente Division of Research, Oakland, California.
Theodore R LevinWalnut Creek Medical Center, Kaiser Permanente Northern California, Walnut Creek, California.
Jeffrey K LeeKaiser Permanente Division of Research, Oakland, California.
Joanne E SchottingerKaiser Permanente Southern California, Pasadena, California.
Wei K ZhaoKaiser Permanente Division of Research, Oakland, California.
Douglas A CorleyKaiser Permanente Division of Research, Oakland, California.
Chyke A DoubeniCenter for Health Equity and Community Engagement Research, Mayo Clinic, Rochester, Minnesota; Department of Family Medicine and Department of General Internal Medicine, Mayo Clinic, Rochester, Minnesota.

Funding

Optimizing Colorectal Cancer Screening PREcision and Outcomes in CommunIty-baSEd Populations (PRECISE)UM1CA222035 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI CHUBAK, JESSICA, CORLEY, DOUGLAS ALLEN · 2018 to 2023
$15.6M
Optimizing the use of colonoscopy for CRC screening in a large community-basedU54CA163262 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI CORLEY, DOUGLAS ALLEN, DOUBENI, CHYKE ABADAMA · 2011 to 2017
$9.6M
Effectiveness of screening for colorectal cancer in average risk adults: Colonoscopy vs. FITR01CA213645 · NCI · UNIVERSITY OF PENNSYLVANIA · PI CORLEY, DOUGLAS ALLEN, DOUBENI, CHYKE ABADAMA · 2017 to 2021
$3.2M
NCI NIH HHS R01 CA213645NCI NIH HHS U54 CA163262NCI NIH HHS UM1 CA222035
6 · The paper itself

Abstract

BACKGROUND AND

aimsProgrammatic colorectal cancer (CRC) screening increases uptake, but the design and resources utilized for such models are not well known. We characterized program components and participation at each step in a large program that used mailed fecal immunochemical testing (FIT) with opportunistic colonoscopy.

methodsMixed-methods with site visits and retrospective cohort analysis of 51-75-year-old adults during 2017 in the Kaiser Permanente Northern California integrated health system.

resultsAmong 1,023,415 screening-eligible individuals, 405,963 (40%) were up to date with screening at baseline, and 507,401 of the 617,452 not up-to-date were mailed a FIT kit. Of the entire cohort (n = 1,023,415), 206,481 (20%) completed FIT within 28 days of mailing, another 61,644 (6%) after a robocall at week 4, and 40,438 others (4%) after a mailed reminder letter at week 6. There were over 800,000 medical record screening alerts generated and about 295,000 FIT kits distributed during patient office visits. About 100,000 FIT kits were ordered during direct-to-patient calls by medical assistants and 111,377 people (11%) completed FIT outside of the automated outreach period. Another 13,560 (1.3%) completed a colonoscopy, sigmoidoscopy, or fecal occult blood test unrelated to FIT. Cumulatively, 839,463 (82%) of those eligible were up to date with screening at the end of the year and 12,091 of 14,450 patients (83.7%) with positive FIT had diagnostic colonoscopy.

conclusionsThe >82% screening participation achieved in this program resulted from a combination of prior endoscopy (40%), large initial response to mailed FIT kits (20%), followed by smaller responses to automated reminders (10%) and personal contact (12%).

Indexed as

Colorectal NeoplasmsOccult BloodAdultAgedColonoscopyEarly Detection of CancerHumansMass ScreeningMiddle AgedRetrospective StudiesColorectal Cancer ScreeningFecal Immunochemical TestsMailed Fecal Tests

Identifiers

PMID33010408
PMCPMC7526597

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.