Evidence map›Paper›PMID 33010401›Full record

ArticleJournal of clinical epidemiology2021

Developing trustworthy recommendations as part of an urgent response (1-2 weeks): a GRADE concept paper.

Elie A Akl, Rebecca L Morgan, Andrew A Rooney, Brandiese Beverly, Srinivasa Vittal Katikireddi, Arnav Agarwal, Brian S Alper, Carlos Alva-Diaz, Laura Amato, Mohammed T Ansari and 27 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical epidemiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Testing guidelines during times of crisis: challenges and limitations of developing rapid and living guidelines.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2023
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Guideline
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

37 authors.

Elie A AklDepartment of Health Research Methods, Evidence, and Impact, McMaster University, McMaster University Medical Centre, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada. Electronic address: ea32@aub.edu.lb.
Rebecca L MorganDepartment of Health Research Methods, Evidence, and Impact, McMaster University, McMaster University Medical Centre, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada.
Andrew A RooneyNational Institute of Environmental Health Science, Durham, NC, USA.
Brandiese BeverlyNational Institute of Environmental Health Science, Durham, NC, USA.
Srinivasa Vittal KatikireddiMRC/CSO Social & Public Health Sciences Unit, University of Glasgow, 200 Renfield Street, Glasgow G2 3AX, UK.
Arnav AgarwalDepartment of Medicine, University of Toronto, C. David Naylor Building, 6 Queen's Park Crescent West, Third Floor, Toronto, ON M5S 3H2, Canada.
Brian S AlperDepartment of Family and Community Medicine, Medical Knowledge Office, EBSCO Information Services, University of Missouri-Columbia School of Medicine, 10 Estes Street, Ipswich, MA 01938, USA.
Carlos Alva-DiazUniversidad Científica del Sur, Facultad de Ciencias de la Salud, Panamericana, Sur km 19, Villa, Lima, Peru.
Laura AmatoDepartment of Epidemiology, Lazio Regional Health Services Rome, via Cristoforo Colombo 112, 00147 Rome, Italy.
Mohammed T AnsariSchool of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Room 101, 600 Peter Morand Crescent, Ottawa, Ontario K1G 5Z3, Canada.
Jan BrozekDepartment of Health Research Methods, Evidence, and Impact, McMaster University, McMaster University Medical Centre, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada.
Derek K ChuDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Rm 3V49 McMaster University Medical Centre, Hamilton, ON L8S 4K1, Canada; Department of Medicine, Rm 3V49 McMaster University Medical Centre, Hamilton, ON L8S 4K1, Canada; The Research Institute of St. Joe's Hamilton, Rm 3V49 McMaster University Medical Centre, Hamilton, ON L8S 4K1, Canada.
Philipp DahmDepartment of Urology, Minneapolis VA Healthcare System, Urology Section, University of Minnesota, One Veterans Drive, Minneapolis, MN 55417, USA.
Andrea J DarziDepartment of Health Research Methods, Evidence, and Impact, McMaster University, McMaster University Medical Centre, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada.
Maicon FalavignaHospital Moinhos de Vento, Porto Alegre, Brazil.
Gerald GartlehnerDepartment for Evidence-based Medicine and Evaluation, RTI International, Danube University, Dr. Karl Dorrekstrasse, Krems Austria, 3040 East Cornwallis Rd, Research Triangle Park, NC, USA.
Hector Pardo-HernandezIberoamerican Cochrane Centre, Sant Pau Biomedical Research Institute (IIB Sant Pau), CIBER de Epidemiología y Salud Pública (CIBERESP), Carrer Sant Antoni Maria Claret, 167, Pavelló 18, Planta Baja (Ground Floor), 08025 Barcelona, Spain.
Valerie KingCenter for Evidence-based Policy, Oregon Health & Science University, 3030 South Moody Ave., Suite 250, Portland, OR 97201, USA.
Jitka KlugarováCzech National Centre for Evidence-Based Healthcare and Knowledge Translation, Institute of Biostatistics and Analyses, Faculty of Medicine, Masaryk University, Brno, Czech Republic.
M W Miranda LangendamAmsterdam UMC, University of Amsterdam, Epidemiology and Data Science, Amsterdam Institute of Public Health, Meibergdreef 9, Amsterdam, the Netherlands.
Craig LockwoodJBI, School of Public Health, University of Adelaide, Level 3/55 King William Road, North Adelaide 5005, Australia.
Manoj MammenDepartment of Medicine, State University of New York at Buffalo, 100 High Street, Buffalo, NY, USA.
Alexander G MathioudakisDivision of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester Academic Health Science Centre, 2nd Floor, Education and Research Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK; The North West Lung Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, 2nd Floor, Education and Research Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK.
Michael McCaulDivision of Epidemiology and Biostatistics, Department of Global Health, Stellenbosch University, Teaching Building, Faculty of Medicine and Health Sciences, Francie van Zijl Drive, Bellville, Western Cape, South Africa.
Joerg J MeerpohlInstitute for Evidence in Medicine, Medical Center & Faculty of Medicine, University of Freiburg, Breisacher Strasse 153, 79110 Freiburg, Germany; Cochrane Germany, Cochrane Germany Foundation, Breisacher Strasse 153, 79110 Freiburg, Germany.
Silvia MinozziDepartment of Biomedical Sciences for Health, University of Milan, Milan, Italy.
Reem A MustafaDepartment of Internal Medicine, University of Kansas Medical Center, 3901 Rainbow Blvd, MS3002, Kansas City, KS 66160, USA; Department of Health Research Methods, Evidence, and Impact, McMaster University, 3901 Rainbow Blvd, MS3002, Kansas City, KS 66160, USA.
Francesco NoninoIRCCS Istituto delle Scienze Neurologiche di Bologna, UOSI Epidemiologia e Statistica, IRCCS-ISNB, Ospedale Bellaria, Via Altura, 3, 40139 Bologna, Italy.
Thomas PiggottDepartment of Health Research Methods, Evidence, and Impact, McMaster University, McMaster University Medical Centre, 1280 Main Street West 2C Area, Hamilton, Ontario L8S 4K1, Canada.
Amir QaseemAmerican College of Physicians, 190 N Independence Mall West, Philadelphia, PA 19087, USA.
John RivaDepartment of Family Medicine, Department of Health Research Methods, Evidence, and Impact, McMaster University, McMaster University Medical Centre, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada.
Rachel RodinPublic Health Agency of Canada, 785 Carling Avenue, Ottawa, Ontario, Canada.
Nigar SekerciogluDepartment of Health Research Methods, Evidence, and Impact, McMaster University, McMaster University Medical Centre, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada.
Nicole SkoetzDepartment I of Internal Medicine and Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Evidence-based Oncology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Kerpener Str. 15, 50935 Cologne, Germany.
Gregory TraversyPublic Health Agency of Canada, Ottawa, Ontario, Canada.
Kris ThayerU.S. Environmental Protection Agency, Office of Research and Development (ORD, Center for Public Health and Environmental Assessment (CPHEA), Mail Code: B243-01, Building: Bldg B (Room B210I), Research Triangle Park, NC 27711, USA.
Holger SchünemannDepartment of Health Research Methods, Evidence, and Impact, McMaster University, McMaster University Medical Centre, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada.

Funding

Integrated Health Assessments for the Division of the National Toxicology ProgramZICES103317 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI ROONEY, ANDREW · 2020 to 2021
$9.6M
Chief Scientist Office SCAF/15/02Chief Scientist Office SPHSU13Chief Scientist Office SPHSU17Department of HealthMedical Research Council MC_UU_00022/2Medical Research Council MC_UU_12017/13
6 · The paper itself

Abstract

objectivesThe aim of this study is to propose an approach for developing trustworthy recommendations as part of urgent responses (1-2 week) in the clinical, public health, and health systems fields. STUDY DESIGN AND

settingWe conducted a review of the literature, outlined a draft approach, refined the concept through iterative discussions, a workshop by the Grading of Recommendations Assessment, Development and Evaluation Rapid Guidelines project group, and obtained feedback from the larger Grading of Recommendations Assessment, Development and Evaluation working group.

resultsA request for developing recommendations within 2 week is the usual trigger for an urgent response. Although the approach builds on the general principles of trustworthy guideline development, we highlight the following steps: (1) assess the level of urgency; (2) assess feasibility; (3) set up the organizational logistics; (4) specify the question(s); (5) collect the information needed; (6) assess the adequacy of identified information; (7) develop the recommendations using one of the 4 potential approaches: adopt existing recommendations, adapt existing recommendations, develop new recommendations using existing adequate systematic review, or develop new recommendations using expert panel input; and (8) consider an updating plan.

conclusionAn urgent response for developing recommendations requires building a cohesive, skilled, and highly motivated multidisciplinary team with the necessary clinical, scientific, and methodological expertise; adapting to shifting needs; complying with the principles of transparency; and properly managing conflicts of interest.

Indexed as

Information ManagementConsensusEvidence-Based MedicineHumansOutcome Assessment, Health CarePractice Guidelines as TopicSystematic Reviews as TopicGRADEPandemicTrustworthy guidelineUrgent recommendation

Identifiers

PMID33010401
PMCPMC7526592

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.