Evidence map›Paper›PMID 33010163›Full record

ArticleNucleic acids research2021

cncRNAdb: a manually curated resource of experimentally supported RNAs with both protein-coding and noncoding function.

Yan Huang, Jing Wang, Yue Zhao, Huafeng Wang, Tianyuan Liu, Yuhe Li, Tianyu Cui, Weiyi Li, Yige Feng, Jiaxin Luo and 5 more

Abstract read
In one paragraph

Article in Nucleic acids research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

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  12. LncRNA-encoded peptides in cancer.Journal of hematology & oncology · 2024
    Review
  13. Article
  14. Article
  15. Review
  16. Article
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  18. Article
  19. A hidden translatome in tumors-the coding lncRNAs.Science China. Life sciences · 2023
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yan HuangShunde Hospital, Southern Medical University (The First People's Hospital of Shunde Foshan), Foshan 528308, China.
Jing WangDepartment of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Yue ZhaoSchool of Basic Medical Sciences & Forensic Medicine, Hangzhou Medical College, Hangzhou 310053, China.
Huafeng WangShunde Hospital, Southern Medical University (The First People's Hospital of Shunde Foshan), Foshan 528308, China.
Tianyuan LiuDepartment of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Yuhe LiDepartment of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Tianyu CuiDepartment of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Weiyi LiDepartment of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Yige FengDepartment of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Jiaxin LuoDepartment of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Jiaqi GongDepartment of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Lin NingDermatology Hospital, Southern Medical University, Guangzhou 510091, China.
Yong ZhangShunde Hospital, Southern Medical University (The First People's Hospital of Shunde Foshan), Foshan 528308, China.
Dong WangShunde Hospital, Southern Medical University (The First People's Hospital of Shunde Foshan), Foshan 528308, China.
Yang ZhangShunde Hospital, Southern Medical University (The First People's Hospital of Shunde Foshan), Foshan 528308, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNA endowed with both protein-coding and noncoding functions is referred to as 'dual-function RNA', 'binary functional RNA (bifunctional RNA)' or 'cncRNA (coding and noncoding RNA)'. Recently, an increasing number of cncRNAs have been identified, including both translated ncRNAs (ncRNAs with coding functions) and untranslated mRNAs (mRNAs with noncoding functions). However, an appropriate database for storing and organizing cncRNAs is still lacking. Here, we developed cncRNAdb, a manually curated database of experimentally supported cncRNAs, which aims to provide a resource for efficient manipulation, browsing and analysis of cncRNAs. The current version of cncRNAdb documents about 2600 manually curated entries of cncRNA functions with experimental evidence, involving more than 2,000 RNAs (including over 1300 translated ncRNAs and over 600 untranslated mRNAs) across over 20 species. In summary, we believe that cncRNAdb will help elucidate the functions and mechanisms of cncRNAs and develop new prediction methods. The database is available at http://www.rna-society.org/cncrnadb/.

Indexed as

3' Untranslated Regions5' Untranslated RegionsAnimalsDatabases, Nucleic AcidDrosophila melanogasterHumansMiceMicroRNAsPan troglodytesRNA, CircularRNA, Long NoncodingRNA, MessengerRNA, RibosomalRNA, Small InterferingRNA, TransferSoftware3' Untranslated Regions5' Untranslated RegionsMicroRNAsRNA, CircularRNA, Long NoncodingRNA, MessengerRNA, RibosomalRNA, Small InterferingRNA, Transfer

Identifiers

PMID33010163
PMCPMC7778915

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.