Evidence map›Paper›PMID 33010129›Full record

ArticleIET nanobiotechnology2020

Biologically-synthesised ZnO/CuO/Ag nanocomposite using propolis extract and coated on the gauze for wound healing applications.

Mahdi Bayrami, Abolfazl Bayrami, Aziz Habibi-Yangjeh, Mohammad Saleh Shafeeyan, Solmaz Feizpoor, Farid Mohammadi Arvanagh, Mohammad Reza Nourani, Ramezan Ali Taheri

Open access · bronzeAbstract read
In one paragraph

Article in IET nanobiotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Design and Biomedical Evaluation of ZnO/Ag/AgApplied biochemistry and biotechnology · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Research Progress on Therapeutic Effect and Mechanism of Propolis on Wound Healing.Evidence-based complementary and alternative medicine : eCAM · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Mahdi BayramiDepartment of Biology, Faculty of Science, University of Mohaghegh Ardabili, Ardabil, Iran.
Abolfazl BayramiDepartment of Biology, Faculty of Science, University of Mohaghegh Ardabili, Ardabil, Iran. a_bayrami@uma.ac.ir.
Aziz Habibi-YangjehDepartment of Chemistry, Faculty of Science, University of Mohaghegh Ardabili, Ardabil, Iran.
Mohammad Saleh ShafeeyanDepartment of Chemical Engineering, Faculty of Engineering, Golestan University, Aliabad Katoul, Iran.
Solmaz FeizpoorDepartment of Chemistry, Faculty of Science, University of Mohaghegh Ardabili, Ardabil, Iran.
Farid Mohammadi ArvanaghDepartment of Biology, Faculty of Science, University of Mohaghegh Ardabili, Ardabil, Iran.
Mohammad Reza NouraniNanobiotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Ramezan Ali TaheriNanobiotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
University of Mohaghegh Ardabili · IRBaqiyatallah University of Medical Sciences · IRGolestan University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wound healing has long been recognised as a major clinical challenge for which stablishing more effective wound therapies is necessary. The generation of metallic nanocomposites using biological compounds is emerging as a new promising strategy for this purpose. In this study, four metallic nanoparticles (NPs) with propolis extract (Ext) and one without propolis including ZnO/Ext, ZnO/Ag/Ext, ZnO/CuO/Ext, ZnO/Ag/CuO/Ext and ZnO/W were prepared by microwave method and assessed for their wound healing activity on excision experimental model of wounds in rats. The developed nanocomposites have been characterised by physico-chemical methods such as X-ray diffraction, scanning electron microscopy, diffuse reflectance UV-vis spectroscopy, Fourier transform infrared spectroscopy, thermogravimetric analysis and Brunauer-Emmett-Teller analyses. The wounded animals treated with the NPs/Ext in five groups for 18 days. Every 6 days, for measuring wound closure rate, three samples of each group were examined for histopathological analysis. The prepared tissue sections were investigated by haematoxylin and Eosin stainings for the formation of epidermis, dermis and muscular and Masson's trichrome staining for the formation of collagen fibres. These findings toughly support the probability of using this new ZnO/Ag/Ext materials dressing for a wound care performance with significant effect compared to other NPs.

Indexed as

AnimalsBandagesCopperEthanolMaleMetal NanoparticlesMicroscopy, Electron, ScanningMicrowavesNanocompositesNanostructuresPlant ExtractsPropolisRatsRats, WistarSilverSpectrophotometry, UltravioletCoppercupric oxideEthanolPlant ExtractsPropolisSilverZinc Oxide

Identifiers

PMID33010129
PMCPMC8676286
OpenAlexW3016440430

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.