ArticleBreast cancer research and treatment2021
Obesity and breast cancer risk for pre- and postmenopausal women among over 6 million Korean women.
Article in Breast cancer research and treatment, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.
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Who cites it
45 citing papers in PubMed, 2 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- Obesity and Risk of Pre- and Postmenopausal Breast Cancer in Africa: A Systematic Review.Current oncology (Toronto, Ont.) · 2025Pooled it
- The relationship between central obesity and risk of breast cancer: a dose-response meta-analysis of 7,989,315 women.Frontiers in nutrition · 2023Pooled it
- Adiposity and risk of breast cancer in 280 000 Chinese women: a prospective cohort study.International journal of epidemiology · 2026Observational
- The effect of body mass index change on breast and uterine cancer risk in middle- and older-aged adults.International journal of cancer · 2026Article
- PCOS and breast cancer risk: hormonal modulation and epidemiological trends.Reproductive health · 2026Review
- Obesity and Cancer: Mechanisms, Epidemiological Evidence, and Potential Risk Reduction.Journal of obesity & metabolic syndrome · 2026Review
- Distinct genetic profiles of obesity have different effects on breast cancer risk: leveraging Mendelian randomisation to interrogate causal pathways and identify mediating proteins.Breast cancer research : BCR · 2026Article
- Modifiable and Nonmodifiable Risk Factors for Breast Cancer: A Comprehensive Scoping Review.International journal of breast cancer · 2026Review
- Clinical factors influencing serum CA125 levels and their implications for diagnosing ovarian tumors.Bioinformation · 2026Article
- Unraveling breast cancer risk with a focus on menopausal status: a large case-control study.Cancer causes & control : CCC · 2025Article
- MRI-Derived Body Composition and Breast Cancer Risk in Postmenopausal Women: UK Biobank Study.Cancers · 2025Article
- Changes in physical activity and diabetes risk after cancer diagnosis: a nationwide cohort study.Journal of cancer survivorship : research and practice · 2025Article
- Analysis of obesity prevalence and trend prediction among professional women in a hospital from 2010 to 2024: a weight management perspective.BMC public health · 2025Article
- Novel Breast Cancer Risk Assessment Tools for Pre- and Postmenopausal Asian Women: Development and Validation in a Nationwide Mammographic Screening Cohort.Cancer research and treatment · 2025Article
- Associations of body mass index and waist circumference with incidence of overall and of 27 site-specific cancers: a population-based retrospective cohort study.Cancer communications (London, England) · 2025Article
- Smoking behavior changes and risk of cardiovascular diseases after cancer diagnosis: a nationwide cohort study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Anthropometry and the Risk of Breast Cancer in Moroccan Women: A Large Multicentric Case-Control Study.Current oncology (Toronto, Ont.) · 2025Article
- SREBP-1 in obesity-induced breast cancer: mechanisms and therapeutic perspectives.Molecular biology reports · 2025Review
- Changes in health behaviors and risk of depression after breast cancer diagnosis and treatment: a nationwide cohort study.Journal of cancer survivorship : research and practice · 2025Article
- Weight change and cardiovascular disease incidence in breast cancer survivors: a nationwide cohort study.Breast cancer research and treatment · 2025Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo examine the association between obesity measured by body mass index (BMI) and waist circumference (WC) according to menopausal status in Korean women.
methodsWe identified 6,467,388 women, using the Korean National Health Insurance System Cohort. Cox-proportional hazard models were used to generate adjusted hazard ratios (aHRs) and 95% confidence intervals (CIs) for breast cancer risk in relation to BMI and WC.
resultsIn postmenopausal women, the risk of breast cancer increased with BMI. Compared to women with a BMI of 18.5-23 kg/m two, the risk of invasive breast cancer was lower in patients with BMI < 18.5 (aHR 0.82, 95% CI 0.75-0.89), while it increased linearly in those with BMI 23-25 (1.11, 1.08-1.14), BMI 25-30 (1.28, 1.25-1.32), and BMI ≥ 30 (1.54,1.47-1.62). In contrast, the risk of breast cancer decreased with BMI in premenopausal women. Compared to women with a BMI of 18.5-23, the risk of IBC was similar in those with a BMI < 18.5 (1.02, 0.94-1.11) and BMI 23-25 (1.01, 0.97-1.05), but was significantly lower in those with a BMI 25-30 (0.95, 0.91-0.98) and BMI ≥ 30 (0.90, 0.82-0.98). A relative increase with BMI was less profound for carcinoma in situ in postmenopausal women, and a relative decrease was more profound in premenopausal women. An analysis using WC showed almost identical results.
conclusionsThere was a positive relationship between obesity and breast cancer in postmenopausal women, and an inverse association in premenopausal women.
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